ID   MQO_RHOPT               Reviewed;         497 AA.
AC   B3QK65;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=Rpal_1548;
OS   Rhodopseudomonas palustris (strain TIE-1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Rhodopseudomonas.
OX   NCBI_TaxID=395960;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TIE-1;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Lang D., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Emerson D.,
RA   Newman D.K., Roden E., Richardson P.;
RT   "Complete sequence of Rhodopseudomonas palustris TIE-1.";
RL   Submitted (MAY-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP001096; ACF00082.1; -; Genomic_DNA.
DR   RefSeq; WP_012495008.1; NC_011004.1.
DR   AlphaFoldDB; B3QK65; -.
DR   EnsemblBacteria; ACF00082; ACF00082; Rpal_1548.
DR   KEGG; rpt:Rpal_1548; -.
DR   HOGENOM; CLU_028151_0_0_5; -.
DR   OMA; RCDNPEV; -.
DR   OrthoDB; 1371190at2; -.
DR   BioCyc; RPAL395960:RPAL_RS07700-MON; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001725; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..497
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000099880"
SQ   SEQUENCE   497 AA;  54182 MW;  9718E653C50AA06F CRC64;
     MSQIPETSDI VLIGAGIMSA TLGTVLKELE PSLSVTMFET LHDCGQESSQ AWNNAGTGHA
     ANCELNYTPQ RSDGSVDISK ALEVNTEFDI SRQLWAHLVG KGAIPDPRAF LHPCPHMSFV
     WGDDNVAFLR QRHREMAAHH CYHGMEFSED PAQIAAWAPL IIEGREPGQP IAATRIISGA
     DVDYGALTHL LVKQLQAQSG FSVHYKHRVV ALARGADGRW LVTVENVTTY ERSTTSARFV
     FAGAGGGSLD ILQKSGIPEG NGYAGFPVSG IWLRCDVDDI SARHHAKVYG KAAHGSPPMS
     VPHLDTRIIG GKRSLLFGPY AGFSSKFLKH GSYADLLRSI EPGNILPMLA VARDDWQLSE
     YLIGQVLQTS EHQFAALQGF FPRAQREDWQ RAVAGQRVQI IKPDPQHTGV LEFGTELLAS
     ADKSFVALLG ASPGASTAAF IAMEVLQKCF DDRLTPDAWL GRLKQMIPTY GIDLKKDADA
     CRDSRAKTAK VLQLDFV