ID   MQO_SERP5               Reviewed;         525 AA.
AC   A8GBY8;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=Spro_1524;
OS   Serratia proteamaculans (strain 568).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=399741;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=568;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Taghavi S., Newman L.,
RA   Vangronsveld J., van der Lelie D., Richardson P.;
RT   "Complete sequence of chromosome of Serratia proteamaculans 568.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000826; ABV40628.1; -; Genomic_DNA.
DR   RefSeq; WP_012005957.1; NC_009832.1.
DR   AlphaFoldDB; A8GBY8; -.
DR   STRING; 399741.Spro_1524; -.
DR   PRIDE; A8GBY8; -.
DR   EnsemblBacteria; ABV40628; ABV40628; Spro_1524.
DR   KEGG; spe:Spro_1524; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..525
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000058628"
SQ   SEQUENCE   525 AA;  58182 MW;  3A828B558AD7846A CRC64;
     MRKILVLIFC LNLFGVTQQA AAEENKTVDV VLIGGGIMSA TLGTYLHELE PNWSIDMYER
     MNGVAEESSN GWNNAGTGHS AFAEMNYTPE KKDGSIDISK AVVVNESFEI SRQFWSYQVK
     NNVLKDPKSF INSVPHMSFV WGDDNVNFLR KRYAALQHST LFRGMEYSED ANQIKQWAPL
     VMDGRDPKQK IAATRMPLGT DVNFGVITHQ LVDTLTKNPN FKLNLSHEVR DIKRNDDNTW
     RVTVADLTRD GKETTVNAKF VFIGAGGASL TLLQKTGIPE AEGYGAFPVG GQFLVTTNPE
     IANQHLAKVY GLASVGSPPM SVPHLDTRML DGKRVLLFGP FATFSGKFLK NGSLFDLLHS
     LSTSNLMPMT HVGLDNFDLV KYLVGQLMMN DDDRFAALKE YFPEAKQADW KLWTAGQRVQ
     IIKKDDEKGG LLQFGTEVVS AKDGSIAALL GASPGASTAA PIMLHLMETV FKDKVATPEW
     QSKLKEIIPS YGHKLNGDIE MTNKIRGYTS SVLQLDYIEV KPETN