ID   MQO_SODGM               Reviewed;         539 AA.
AC   Q2NS49;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 87.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=SG1751;
OS   Sodalis glossinidius (strain morsitans).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Bruguierivoracaceae; Sodalis.
OX   NCBI_TaxID=343509;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=morsitans;
RX   PubMed=16365377; DOI=10.1101/gr.4106106;
RA   Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA   Aksoy S.;
RT   "Massive genome erosion and functional adaptations provide insights into
RT   the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL   Genome Res. 16:149-156(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; AP008232; BAE75026.1; -; Genomic_DNA.
DR   RefSeq; WP_011411575.1; NZ_LN854557.1.
DR   AlphaFoldDB; Q2NS49; -.
DR   STRING; 343509.SG1751; -.
DR   EnsemblBacteria; BAE75026; BAE75026; SG1751.
DR   KEGG; sgl:SG1751; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; VEINYNH; -.
DR   OrthoDB; 1371190at2; -.
DR   BioCyc; SGLO343509:SGP1_RS15950-MON; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001932; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..539
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325513"
SQ   SEQUENCE   539 AA;  59147 MW;  927BF35D8FD87A5D CRC64;
     MKENFIAALG MTVSASAKQH QVVDNPPVDI ILIGGGVMSA TLGTYLKALE PGWTIHMYER
     LEKTAEESSN GWNNAGTGHA AFCELNYTTL SPAGSVDISK AVAVNESFEI SRQFWAYLVK
     QKILTNPQSF INNVPHMSFV WGEDNIRFLR QRFDALQTST LFRGMEYSEN PQQIREWAPL
     VMDGRDTFQK VAATRMAMGT DVNFGEMTQQ LLAALQQYPQ FHLHLQHDVV DIKRNADQTW
     SVRVADHSNG GRQSTVCARH VFIGGGGASL TLLQKSGIPE VNGYAGFPVG GQFLVATNPE
     VVGHHHAKVY GKASVGAPPM SVPHIDTRIL DGKQALLFGP FATFSSKFLK RGSWLDLFHS
     LTRQNLLPML RVGLDNFGLM RYLIGQLLMS DKDRLNALRE YYPQATMADW SLIEAGQRVQ
     VIKKDAGKGG ILQFGTEVVS SADGSLSVLL GASPGASTAA PIMLELLASM FKEQVTTDAW
     QRKLKEMVPS YGQTINGNLA LTNEIRLSTS EVLGLTYIEA KPLPGEPADG KWEGLQKAM