ID   MQO_SYNR3               Reviewed;         477 AA.
AC   A5GRE3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212};
GN   OrderedLocusNames=SynRCC307_0549;
OS   Synechococcus sp. (strain RCC307).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=316278;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RCC307;
RG   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CT978603; CAK27452.1; -; Genomic_DNA.
DR   RefSeq; WP_011934967.1; NC_009482.1.
DR   AlphaFoldDB; A5GRE3; -.
DR   STRING; 316278.SynRCC307_0549; -.
DR   EnsemblBacteria; CAK27452; CAK27452; SynRCC307_0549.
DR   KEGG; syr:SynRCC307_0549; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_3; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000001115; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..477
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325515"
SQ   SEQUENCE   477 AA;  50985 MW;  8710737E2C97F3A0 CRC64;
     MTDRYDAVLV GAGIMGATLA ALLHELDPAM RLLMLERLDG PALESSAAAN NAGTGHAANC
     ELNYTPQQAD GSVATAKALA INAAFERSLE FWATLRERGE LDTPAFLNSV PHISFVWGQG
     DVAFLRQRHQ QLSALPAFAG MEWSSDPAEL AEWMPLVMQG RGASEPVAAT RISRGTDVDF
     GSLTRLYLQD LQRSGALELR TGCEVNDLTR KSNGDWSVEL AGGERVQTPF VFLGAGGGAL
     PLLQRSTIPE AKAFAGFPVS GQWLVCGDNQ LASRHLAKVY GKAKVGAPPM SVPHLDTRFI
     NGERSLLFGP FAGFSTKFLK QGSLLDLPRS VRIGNLLPML QVGAGNFPLV QYLINQLRQS
     PEQRLEALQQ FLPQAEASDW TLSVAGQRVQ IIKNGPKGGQ LQLGTEVVAA ADGSLAALLG
     ASPGASTAVT TMLEVLERCF ASRLATPAWQ ERLKALFPSW GGDVLSSRSR NTAVLGL