ID   MQO_SYNS9               Reviewed;         502 AA.
AC   Q3AWX1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212};
GN   OrderedLocusNames=Syncc9902_1584;
OS   Synechococcus sp. (strain CC9902).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=316279;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9902;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Martinez M., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Synechococcus sp. CC9902.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP000097; ABB26542.1; -; Genomic_DNA.
DR   RefSeq; WP_011360359.1; NC_007513.1.
DR   AlphaFoldDB; Q3AWX1; -.
DR   STRING; 316279.Syncc9902_1584; -.
DR   EnsemblBacteria; ABB26542; ABB26542; Syncc9902_1584.
DR   KEGG; sye:Syncc9902_1584; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_3; -.
DR   OMA; PHLDTRW; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000002712; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..502
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000023817"
SQ   SEQUENCE   502 AA;  54805 MW;  5ECDCA7884944FA1 CRC64;
     MQNDGTFDPE ASYDAVLVGA GIMSATLAAL LHELDPQLRL LLVERLEAPA LESSAAVNNA
     GTGHAANCEL NYTPMQPNGR VATDKAVAIN AAFERSLEFW GSLLERGRLT STDFLHRAAH
     ISAVWSPANI AFLRQRFEQL KDIPAFAEMR WTEDRQDLAE WMPLVMEGRD PNQAVAATRI
     ERGTDVDFGA LTRAYLLPLQ SSGALTVQYG TEVSNLKRLR RPNMTEGDWR VITKGPSGRR
     EVRAPFVFLG AGGGALPLLQ RSGIPEGDDF AGFPVSGLWL VCNDADLAEQ QRAKVYGKAA
     VGAPPMSVPH LDTRWMDGRR SLLFGPFAGF SSKFLKQGSL LDLPASVRPT NLLPMLQVGA
     TNIELVRYLI NQLRQTPDQR FDALRDFLPT ARQDDWSLSV AGQRVQIIKR SKEGGRLQLG
     TEVVAASDGS LAALLGASPG ASTAVTIMLE VLQRCFPERL ASADWQARLK ALLPSFYSDP
     KSDPDVLKGM RERSDGLLGL SR