ID   MQO_SYNSC               Reviewed;         502 AA.
AC   Q3ALG7;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212};
GN   OrderedLocusNames=Syncc9605_0797;
OS   Synechococcus sp. (strain CC9605).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=110662;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC9605;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Schmutz J., Martinez M., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Synechococcus sp. CC9605.";
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABB34565.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000110; ABB34565.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_041434464.1; NC_007516.1.
DR   AlphaFoldDB; Q3ALG7; -.
DR   STRING; 110662.Syncc9605_0797; -.
DR   PRIDE; Q3ALG7; -.
DR   EnsemblBacteria; ABB34565; ABB34565; Syncc9605_0797.
DR   KEGG; syd:Syncc9605_0797; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_3; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.
FT   CHAIN           1..502
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_0000325514"
SQ   SEQUENCE   502 AA;  54791 MW;  DE2E8AE8A3628673 CRC64;
     MQHDGSFNPE ARFDAVLVGA GIMSATLAAL LHELDTQLRI LLVERLEAPA LESSAAVNNA
     GTGHAANCEL NYTPIQADGT VATAKAVAIN TSFERSLEFW SSLQERGDLD TSSFLHQAAH
     ISAVWTPENI AFLRQRFSQL KELPAFARMR WSEDQSELTE WMPLVMAGRD LKQPVAATRI
     DRGTDVDFGS LTRAYLMPLQ QSGALSVEYG TQVHDLKRLR HSDMTEADWR VVLKGPSGKK
     EVRAPFVFLG AGGGALPLLQ RSGIPEAADF AGFPVSGLWL VCGDAQLADR QRAKVYGKAA
     VGAPPMSVPH LDTRWVDGKR SLLFGPFAGF SSKFLKQGSL LDLPASVRAT NLLPMLQVGA
     TNFELVQYLI NQLRQSPTQR HEALQQFMPT ARAEDWTLSV AGQRVQIIKR SKQGGRLQLG
     TEVVASGDGS LAALLGASPG ASTAVTIMLE VLERCFKQRL DSDAWQQRLQ ALLPSIHEDP
     HQDPQVLNRM RERSDALLGL TA