ID   MQO_TOLAT               Reviewed;         497 AA.
AC   C4LEV7;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Probable malate:quinone oxidoreductase {ECO:0000255|HAMAP-Rule:MF_00212};
DE            EC=1.1.5.4 {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=MQO {ECO:0000255|HAMAP-Rule:MF_00212};
DE   AltName: Full=Malate dehydrogenase [quinone] {ECO:0000255|HAMAP-Rule:MF_00212};
GN   Name=mqo {ECO:0000255|HAMAP-Rule:MF_00212}; OrderedLocusNames=Tola_1513;
OS   Tolumonas auensis (strain DSM 9187 / TA4).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Tolumonas.
OX   NCBI_TaxID=595494;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 9187 / TA4;
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D.,
RA   Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Spring S.,
RA   Beller H.;
RT   "Complete sequence of Tolumonas auensis DSM 9187.";
RL   Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(S)-malate + a quinone = a quinol + oxaloacetate;
CC         Xref=Rhea:RHEA:46012, ChEBI:CHEBI:15589, ChEBI:CHEBI:16452,
CC         ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.1.5.4;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00212};
CC   -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle;
CC       oxaloacetate from (S)-malate (quinone route): step 1/1.
CC       {ECO:0000255|HAMAP-Rule:MF_00212}.
CC   -!- SIMILARITY: Belongs to the MQO family. {ECO:0000255|HAMAP-
CC       Rule:MF_00212}.
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DR   EMBL; CP001616; ACQ93124.1; -; Genomic_DNA.
DR   RefSeq; WP_015878596.1; NC_012691.1.
DR   AlphaFoldDB; C4LEV7; -.
DR   STRING; 595494.Tola_1513; -.
DR   EnsemblBacteria; ACQ93124; ACQ93124; Tola_1513.
DR   KEGG; tau:Tola_1513; -.
DR   eggNOG; COG0579; Bacteria.
DR   HOGENOM; CLU_028151_0_0_6; -.
DR   OMA; RCDNPEV; -.
DR   OrthoDB; 1371190at2; -.
DR   UniPathway; UPA00223; UER01008.
DR   Proteomes; UP000009073; Chromosome.
DR   GO; GO:0052589; F:malate dehydrogenase (menaquinone) activity; IEA:UniProtKB-EC.
DR   GO; GO:0008924; F:malate dehydrogenase (quinone) activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.50.50.60; -; 1.
DR   HAMAP; MF_00212; MQO; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR006231; MQO.
DR   Pfam; PF06039; Mqo; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   TIGRFAMs; TIGR01320; mal_quin_oxido; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome;
KW   Tricarboxylic acid cycle.
FT   CHAIN           1..497
FT                   /note="Probable malate:quinone oxidoreductase"
FT                   /id="PRO_1000204204"
SQ   SEQUENCE   497 AA;  54804 MW;  25240F9F6BDFD8D5 CRC64;
     MASIHADVTL VGGGIMSATL AMLIHRLDPA LHICMIEQLP DIALESSGAL NNAGTGHAGY
     CELNYTPHDK DGNVLIQRAL EINAAFEVSL QFWSHLVNAD RENITPSSFI NRVPHLSAVW
     GQKDIDFLKA RYTLLKSHHL FSEMKWSEDE QTLADWMPLM MKGRQAEPKL AATRVEHGAD
     VNFGALTRIL VSYLQKNANF ELLTNTRVVD LHRAHGAKKP WAVKVKNQNS AAKQTIESPF
     VFLGAGGVAL HLLQNSGIEE AAGYGGFPVS GQWLICQNQD LIRQHHAKVY SLAAVGAPPM
     SVPHLDTRII NGKPSLLFGP YAGFTTKFLK HGSPFDLAKS VRPHNLKSLI GAGKNNFDLT
     KYLVKEVFQT HSQRMQSLEA FIPNARAEDW QLAHAGKRVQ IIKRCHHKWG KLEFGTEIVA
     AEDGSLAALL GASPGASVSV KTMLDVLERC FPQQMQSAEW QDKLKTMIPS YGRSLINDAN
     LSASVRRYTL DTLKLSS