MRAS1_HUMAN
ID MRAS1_HUMAN Reviewed; 158 AA.
AC Q2M3A8; Q6TF48; Q8N7R8; Q8N9X7;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 21-FEB-2006, sequence version 1.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Putative uncharacterized protein MRGPRG-AS1;
DE AltName: Full=MRGPRG antisense RNA 1;
DE AltName: Full=MRGPRG antisense gene protein 1;
GN Name=MRGPRG-AS1; Synonyms=C11orf36; ORFNames=HSD-40, HSD40;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANTS ALA-6; PHE-135 AND
RP VAL-142.
RC TISSUE=Testis;
RA Yang C.B., Miao S.Y., Zhang X.D., Qiao Y., Liang G., Wang L.F.;
RT "A new spermatogenesis-related gene.";
RL Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANTS PHE-135 AND VAL-142.
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.-W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.-S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- CAUTION: Product of a dubious CDS prediction. {ECO:0000305}.
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DR EMBL; AY422795; AAR84193.1; -; mRNA.
DR EMBL; AK093421; BAC04158.1; -; mRNA.
DR EMBL; AK097749; BAC05159.1; -; mRNA.
DR EMBL; AC109309; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC104971; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; BC104973; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q2M3A8; -.
DR BioMuta; HGNC:26691; -.
DR DMDM; 115502126; -.
DR MassIVE; Q2M3A8; -.
DR PRIDE; Q2M3A8; -.
DR ProteomicsDB; 61368; -.
DR GeneCards; MRGPRG-AS1; -.
DR HGNC; HGNC:26691; MRGPRG-AS1.
DR neXtProt; NX_Q2M3A8; -.
DR InParanoid; Q2M3A8; -.
DR PathwayCommons; Q2M3A8; -.
DR Pharos; Q2M3A8; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q2M3A8; protein.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..158
FT /note="Putative uncharacterized protein MRGPRG-AS1"
FT /id="PRO_0000251725"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 66..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 111..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 6
FT /note="E -> A (in dbSNP:rs11026002)"
FT /evidence="ECO:0000269|Ref.1"
FT /id="VAR_027707"
FT VARIANT 135
FT /note="S -> F (in dbSNP:rs11026004)"
FT /evidence="ECO:0000269|PubMed:14702039, ECO:0000269|Ref.1"
FT /id="VAR_027708"
FT VARIANT 142
FT /note="G -> V (in dbSNP:rs12280457)"
FT /evidence="ECO:0000269|PubMed:14702039, ECO:0000269|Ref.1"
FT /id="VAR_027709"
FT CONFLICT 3
FT /note="L -> S (in Ref. 2; BAC04158)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 158 AA; 16456 MW; 5632F50B9DFEBF55 CRC64;
MDLASEITSA TQTSSLCSSG RGHAGYPAPG IVAHGFETHG TARVAQGHLL PPCLLPPPQM
PVLAALRDLS RRGSTSSSRS PSRPVSTSAS KPCLPASCLG ETWSISINLV GSSGHLQSPG
AQRDAQRETG CLGPSWLPHH QGRDEELSLS HSAQGEEF
