ARNF_SALAR
ID ARNF_SALAR Reviewed; 139 AA.
AC A9MJC2;
DT 01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 55.
DE RecName: Full=Putative 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF;
DE Short=L-Ara4N-phosphoundecaprenol flippase subunit ArnF;
DE AltName: Full=Undecaprenyl phosphate-aminoarabinose flippase subunit ArnF;
GN Name=arnF; OrderedLocusNames=SARI_00596;
OS Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=41514;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-731 / CDC346-86 / RSK2980;
RG The Salmonella enterica serovar Arizonae Genome Sequencing Project;
RA McClelland M., Sanderson E.K., Porwollik S., Spieth J., Clifton W.S.,
RA Fulton R., Chunyan W., Wollam A., Shah N., Pepin K., Bhonagiri V., Nash W.,
RA Johnson M., Thiruvilangam P., Wilson R.;
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Translocates 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
CC (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the
CC periplasmic side of the inner membrane. {ECO:0000250}.
CC -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC biosynthesis.
CC -!- SUBUNIT: Heterodimer of ArnE and ArnF. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255}; Multi-pass
CC membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the ArnF family. {ECO:0000305}.
CC -!- CAUTION: Compared to other bacterial ArnF, it has a divergent C-
CC terminal domain. The upstream arnE gene has a premature stop codon and
CC an internal deletion; as the 2 proteins form a heterodimer, ArnF
CC probably does not accumulate to high levels. {ECO:0000305|Ref.1}.
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DR EMBL; CP000880; ABX20522.1; -; Genomic_DNA.
DR AlphaFoldDB; A9MJC2; -.
DR STRING; 41514.SARI_00596; -.
DR EnsemblBacteria; ABX20522; ABX20522; SARI_00596.
DR KEGG; ses:SARI_00596; -.
DR HOGENOM; CLU_1843687_0_0_6; -.
DR OMA; AQLGMRW; -.
DR UniPathway; UPA00030; -.
DR Proteomes; UP000002084; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009245; P:lipid A biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR InterPro; IPR000390; Small_drug/metabolite_transptr.
DR PANTHER; PTHR30561; PTHR30561; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Lipid A biosynthesis;
KW Lipid biosynthesis; Lipid metabolism; Lipopolysaccharide biosynthesis;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..139
FT /note="Putative 4-amino-4-deoxy-L-arabinose-
FT phosphoundecaprenol flippase subunit ArnF"
FT /id="PRO_0000382016"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..90
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 139 AA; 15023 MW; 79DD2BDA5ABE0B32 CRC64;
MGVMWGLISV AIASLAQLSL GFSMMRLPSI AHPLAFIAGL GAFTTATLAL FAGLAGYLIP
VSCWQKTLHS LALSKTYALL SLSYVLVRVV TRSVRRFLSK SDARRIVHCG GDNADFPARQ
LMMACASTAA IRRRNNIEH
