MRAZ_ENTFA
ID MRAZ_ENTFA Reviewed; 143 AA.
AC O07103;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 23-APR-2003, sequence version 2.
DT 03-AUG-2022, entry version 118.
DE RecName: Full=Transcriptional regulator MraZ;
GN Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008}; OrderedLocusNames=EF_0988;
OS Enterococcus faecalis (strain ATCC 700802 / V583).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=226185;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=A24836;
RX PubMed=9287029; DOI=10.1128/jb.179.17.5632-5635.1997;
RA Pucci M.J., Thanassi J.A., Discotto L.F., Kessler R.E., Dougherty T.J.;
RT "Identification and characterization of cell wall-cell division gene
RT clusters in pathogenic Gram-positive cocci.";
RL J. Bacteriol. 179:5632-5635(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700802 / V583;
RX PubMed=12663927; DOI=10.1126/science.1080613;
RA Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT faecalis.";
RL Science 299:2071-2074(2003).
CC -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_01008}.
CC -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC Rule:MF_01008}.
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DR EMBL; U94707; AAC45630.1; -; Genomic_DNA.
DR EMBL; AE016830; AAO80794.1; -; Genomic_DNA.
DR RefSeq; NP_814724.1; NC_004668.1.
DR RefSeq; WP_002355890.1; NZ_KE136527.1.
DR AlphaFoldDB; O07103; -.
DR SMR; O07103; -.
DR STRING; 226185.EF_0988; -.
DR EnsemblBacteria; AAO80794; AAO80794; EF_0988.
DR KEGG; efa:EF0988; -.
DR PATRIC; fig|226185.45.peg.3194; -.
DR eggNOG; COG2001; Bacteria.
DR HOGENOM; CLU_107907_0_5_9; -.
DR OMA; RGQERCL; -.
DR Proteomes; UP000001415; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd16321; MraZ_C; 1.
DR CDD; cd16320; MraZ_N; 1.
DR Gene3D; 3.40.1550.20; -; 1.
DR HAMAP; MF_01008; MraZ; 1.
DR InterPro; IPR003444; MraZ.
DR InterPro; IPR035644; MraZ_C.
DR InterPro; IPR020603; MraZ_dom.
DR InterPro; IPR035642; MraZ_N.
DR InterPro; IPR038619; MraZ_sf.
DR InterPro; IPR007159; SpoVT-AbrB_dom.
DR InterPro; IPR037914; SpoVT-AbrB_sf.
DR PANTHER; PTHR34701; PTHR34701; 1.
DR Pfam; PF02381; MraZ; 2.
DR SUPFAM; SSF89447; SSF89447; 1.
DR TIGRFAMs; TIGR00242; TIGR00242; 1.
DR PROSITE; PS51740; SPOVT_ABRB; 2.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..143
FT /note="Transcriptional regulator MraZ"
FT /id="PRO_0000108482"
FT DOMAIN 5..47
FT /note="SpoVT-AbrB 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
FT DOMAIN 76..119
FT /note="SpoVT-AbrB 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
FT CONFLICT 111
FT /note="R -> G (in Ref. 1; AAC45630)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 143 AA; 16472 MW; F09A58570E893291 CRC64;
MLMGEYQHNI DAKGRLIVPS KFREELGEKF VVTRGMDGCL FGYPLNEWSQ LEAKLQEMPL
AKKDARTFVR FFYSAATECE IDKQGRINIP ANLRTHASLE KGCVVIGVSN RIEIWSDERW
HAFSDEAEEN FDELAETMID FGF
