ID   MRAZ_ESCF3              Reviewed;         152 AA.
AC   B7LWG9;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Transcriptional regulator MraZ;
GN   Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008}; OrderedLocusNames=EFER_0103;
OS   Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM
OS   14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585054;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35469 / DSM 13698 / BCRC 15582 / CCUG 18766 / IAM 14443 / JCM
RC   21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Negatively regulates its own expression and that of the
CC       subsequent genes in the proximal part of the division and cell wall
CC       (dcw) gene cluster. Acts by binding directly to DNA. May also regulate
CC       the expression of genes outside the dcw cluster. {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
CC   -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01008}.
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DR   EMBL; CU928158; CAQ87686.1; -; Genomic_DNA.
DR   RefSeq; WP_000488287.1; NC_011740.1.
DR   AlphaFoldDB; B7LWG9; -.
DR   SMR; B7LWG9; -.
DR   EnsemblBacteria; CAQ87686; CAQ87686; EFER_0103.
DR   GeneID; 60903308; -.
DR   KEGG; efe:EFER_0103; -.
DR   HOGENOM; CLU_107907_2_0_6; -.
DR   OMA; RGQERCL; -.
DR   OrthoDB; 1684767at2; -.
DR   BioCyc; EFER585054:EFER_RS00760-MON; -.
DR   Proteomes; UP000000745; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR   GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd16321; MraZ_C; 1.
DR   CDD; cd16320; MraZ_N; 1.
DR   Gene3D; 3.40.1550.20; -; 1.
DR   HAMAP; MF_01008; MraZ; 1.
DR   InterPro; IPR003444; MraZ.
DR   InterPro; IPR035644; MraZ_C.
DR   InterPro; IPR020603; MraZ_dom.
DR   InterPro; IPR035642; MraZ_N.
DR   InterPro; IPR038619; MraZ_sf.
DR   InterPro; IPR007159; SpoVT-AbrB_dom.
DR   InterPro; IPR037914; SpoVT-AbrB_sf.
DR   PANTHER; PTHR34701; PTHR34701; 1.
DR   Pfam; PF02381; MraZ; 2.
DR   SUPFAM; SSF89447; SSF89447; 1.
DR   TIGRFAMs; TIGR00242; TIGR00242; 1.
DR   PROSITE; PS51740; SPOVT_ABRB; 2.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Repeat; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..152
FT                   /note="Transcriptional regulator MraZ"
FT                   /id="PRO_1000134798"
FT   DOMAIN          5..52
FT                   /note="SpoVT-AbrB 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
FT   DOMAIN          81..124
FT                   /note="SpoVT-AbrB 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
SQ   SEQUENCE   152 AA;  17452 MW;  7F44E3CC789B8E41 CRC64;
     MFRGATLVNL DSKGRLSVPT RYREELLGNA AGQMVCTIDI HHPCLLLYPL PEWEIIEHKL
     SRLSSMNPVE RRVQRLLLGH ASECQLDNAG RLLIAPVLRQ HAGLTKEVML VGQFNKFELW
     DETTWHQQVR EDIDAEQSIT ENLSERLQDL SL