MRAZ_SHIDS
ID MRAZ_SHIDS Reviewed; 152 AA.
AC Q32K11;
DT 04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT 06-DEC-2005, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Transcriptional regulator MraZ;
GN Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008}; OrderedLocusNames=SDY_0111;
OS Shigella dysenteriae serotype 1 (strain Sd197).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=300267;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Sd197;
RX PubMed=16275786; DOI=10.1093/nar/gki954;
RA Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA Jin Q.;
RT "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT bacillary dysentery.";
RL Nucleic Acids Res. 33:6445-6458(2005).
CC -!- FUNCTION: Negatively regulates its own expression and that of the
CC subsequent genes in the proximal part of the division and cell wall
CC (dcw) gene cluster. Acts by binding directly to DNA. May also regulate
CC the expression of genes outside the dcw cluster. {ECO:0000255|HAMAP-
CC Rule:MF_01008}.
CC -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_01008}.
CC -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC Rule:MF_01008}.
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DR EMBL; CP000034; ABB60346.1; -; Genomic_DNA.
DR RefSeq; WP_011378541.1; NC_007606.1.
DR RefSeq; YP_401835.1; NC_007606.1.
DR AlphaFoldDB; Q32K11; -.
DR SMR; Q32K11; -.
DR STRING; 300267.SDY_0111; -.
DR EnsemblBacteria; ABB60346; ABB60346; SDY_0111.
DR KEGG; sdy:SDY_0111; -.
DR PATRIC; fig|300267.13.peg.130; -.
DR HOGENOM; CLU_107907_2_0_6; -.
DR OMA; RGQERCL; -.
DR Proteomes; UP000002716; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd16321; MraZ_C; 1.
DR CDD; cd16320; MraZ_N; 1.
DR Gene3D; 3.40.1550.20; -; 1.
DR HAMAP; MF_01008; MraZ; 1.
DR InterPro; IPR003444; MraZ.
DR InterPro; IPR035644; MraZ_C.
DR InterPro; IPR020603; MraZ_dom.
DR InterPro; IPR035642; MraZ_N.
DR InterPro; IPR038619; MraZ_sf.
DR InterPro; IPR007159; SpoVT-AbrB_dom.
DR InterPro; IPR037914; SpoVT-AbrB_sf.
DR PANTHER; PTHR34701; PTHR34701; 1.
DR Pfam; PF02381; MraZ; 2.
DR SUPFAM; SSF89447; SSF89447; 1.
DR TIGRFAMs; TIGR00242; TIGR00242; 1.
DR PROSITE; PS51740; SPOVT_ABRB; 2.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Reference proteome; Repeat; Repressor;
KW Transcription; Transcription regulation.
FT CHAIN 1..152
FT /note="Transcriptional regulator MraZ"
FT /id="PRO_0000230109"
FT DOMAIN 5..52
FT /note="SpoVT-AbrB 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
FT DOMAIN 81..124
FT /note="SpoVT-AbrB 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
SQ SEQUENCE 152 AA; 17370 MW; 4AD8AD9418EEF756 CRC64;
MFRGATLVNL DSKGRLSVPT RYREQLLENA AGQMVCTIDI HHPCLLLYPL PEWEIIEQKL
PRLSSMNPVE RRVQRLLLGH ASECQMDGAG RLLIAPVLRQ HAGLTKEVML VGQFNKFELW
DETTWHQQVK EDIDAEQLAT GDLSERLQDL SL