MRAZ_TREPA
ID MRAZ_TREPA Reviewed; 149 AA.
AC O83398;
DT 03-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=Transcriptional regulator MraZ;
GN Name=mraZ {ECO:0000255|HAMAP-Rule:MF_01008}; OrderedLocusNames=TP_0383;
OS Treponema pallidum (strain Nichols).
OC Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX NCBI_TaxID=243276;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nichols;
RX PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA Venter J.C.;
RT "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL Science 281:375-388(1998).
CC -!- SUBUNIT: Forms oligomers. {ECO:0000255|HAMAP-Rule:MF_01008}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, nucleoid {ECO:0000255|HAMAP-
CC Rule:MF_01008}.
CC -!- SIMILARITY: Belongs to the MraZ family. {ECO:0000255|HAMAP-
CC Rule:MF_01008}.
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DR EMBL; AE000520; AAC65367.1; -; Genomic_DNA.
DR PIR; A71331; A71331.
DR RefSeq; WP_010881831.1; NC_021490.2.
DR AlphaFoldDB; O83398; -.
DR SMR; O83398; -.
DR IntAct; O83398; 67.
DR STRING; 243276.TPANIC_0383; -.
DR EnsemblBacteria; AAC65367; AAC65367; TP_0383.
DR KEGG; tpa:TP_0383; -.
DR eggNOG; COG2001; Bacteria.
DR HOGENOM; CLU_107907_0_5_12; -.
DR OMA; RGQERCL; -.
DR OrthoDB; 1684767at2; -.
DR Proteomes; UP000000811; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-UniRule.
DR GO; GO:0009295; C:nucleoid; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR CDD; cd16321; MraZ_C; 1.
DR CDD; cd16320; MraZ_N; 1.
DR Gene3D; 3.40.1550.20; -; 1.
DR HAMAP; MF_01008; MraZ; 1.
DR InterPro; IPR003444; MraZ.
DR InterPro; IPR035644; MraZ_C.
DR InterPro; IPR020603; MraZ_dom.
DR InterPro; IPR035642; MraZ_N.
DR InterPro; IPR038619; MraZ_sf.
DR InterPro; IPR007159; SpoVT-AbrB_dom.
DR InterPro; IPR037914; SpoVT-AbrB_sf.
DR PANTHER; PTHR34701; PTHR34701; 1.
DR Pfam; PF02381; MraZ; 2.
DR SUPFAM; SSF89447; SSF89447; 1.
DR TIGRFAMs; TIGR00242; TIGR00242; 1.
DR PROSITE; PS51740; SPOVT_ABRB; 2.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Reference proteome; Repeat; Transcription;
KW Transcription regulation.
FT CHAIN 1..149
FT /note="Transcriptional regulator MraZ"
FT /id="PRO_0000108552"
FT DOMAIN 9..52
FT /note="SpoVT-AbrB 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
FT DOMAIN 82..125
FT /note="SpoVT-AbrB 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
SQ SEQUENCE 149 AA; 17096 MW; 9CA9465EC5AAE850 CRC64;
MEDNAFTGAY SYNLDEKGRL MLPARLRVAL SDTRLVLTCA IESCLWVFPR AQWDRFSSQI
SARASLFHAP SRAVLRRLIA PAQEVELDRA WRLFIPPSLR EYAALEKDCL ILGLSHCLEI
WDRARYRAYL AESEADFRAG TETLQDLCL