ID   MRCOL_HUMAN             Reviewed;         285 AA.
AC   A0A1B0GUY1;
DT   28-FEB-2018, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 1.
DT   03-AUG-2022, entry version 30.
DE   RecName: Full=MARCO-like protein {ECO:0000305};
DE   Flags: Precursor;
GN   Name=MARCOL {ECO:0000312|HGNC:HGNC:53644};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA   Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA   Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA   Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA   Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA   Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA   Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-66.
RC   TISSUE=Liver;
RA   Xu C.S.;
RT   "Liver regeneration after PH.";
RL   Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AC011346; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; DW438845; -; NOT_ANNOTATED_CDS; mRNA.
DR   CCDS; CCDS87333.1; -.
DR   RefSeq; XP_011536019.1; XM_011537717.2.
DR   AlphaFoldDB; A0A1B0GUY1; -.
DR   GlyGen; A0A1B0GUY1; 1 site.
DR   BioMuta; ENSG00000248109; -.
DR   jPOST; A0A1B0GUY1; -.
DR   MassIVE; A0A1B0GUY1; -.
DR   PeptideAtlas; A0A1B0GUY1; -.
DR   Ensembl; ENST00000638089.2; ENSP00000490292.1; ENSG00000248109.3.
DR   MANE-Select; ENST00000638089.2; ENSP00000490292.1; NM_001363511.2; NP_001350440.1.
DR   GeneCards; MARCOL; -.
DR   HGNC; HGNC:53644; MARCOL.
DR   HPA; ENSG00000248109; Tissue enhanced (epididymis, urinary bladder).
DR   neXtProt; NX_A0A1B0GUY1; -.
DR   OpenTargets; ENSG00000248109; -.
DR   VEuPathDB; HostDB:ENSG00000248109; -.
DR   GeneTree; ENSGT00740000116871; -.
DR   OMA; FHQQGRP; -.
DR   OrthoDB; 1361406at2759; -.
DR   Pharos; A0A1B0GUY1; Tdark.
DR   PRO; PR:A0A1B0GUY1; -.
DR   Proteomes; UP000005640; Chromosome 5.
DR   RNAct; A0A1B0GUY1; protein.
DR   Bgee; ENSG00000248109; Expressed in corpus callosum and 19 other tissues.
DR   ExpressionAtlas; A0A1B0GUY1; baseline and differential.
DR   GO; GO:0031012; C:extracellular matrix; IBA:GO_Central.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0005201; F:extracellular matrix structural constituent; IBA:GO_Central.
DR   GO; GO:0030198; P:extracellular matrix organization; IBA:GO_Central.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..285
FT                   /note="MARCO-like protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5008408671"
FT   REGION          47..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          91..285
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..73
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        101..285
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        24
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255, ECO:0000255|PROSITE-
FT                   ProRule:PRU00498"
SQ   SEQUENCE   285 AA;  29775 MW;  3886708FEEDFAF4A CRC64;
     MRAFIFFLFM LLAMFSASST QISNTSVFKL EENPKPALIL EEKNEANHLG GQRDSNKQGG
     SYTQGNPGTF RLQGQPGYFN KLEKPRHFKQ GRAGVLNQPG ILKNSGKSNQ KGNPESSNKQ
     ENSGSSSQLG RPGISTQQGN PGSSDQQEKP GSFSQKVMVG SSSQQGKPGS SSQHGNLGSS
     TQKGNLGSSS LQGHLGLSSH QGKPESSGQQ GKPGSSSQQG NLGTSGQQEK PGSSSQQGKP
     GLSSHQGKPG SSSQQGNLHL SSQQGNQGPS SKQRKPGSSS RQGNL