ID   MREC_GEOSE              Reviewed;         290 AA.
AC   P84480;
DT   11-JUL-2012, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Cell shape-determining protein MreC {ECO:0000312|PIR:JC4595};
DE   AltName: Full=Cell shape protein MreC {ECO:0000250|UniProtKB:Q01466};
DE   AltName: Full=Rod shape-determining protein MreC {ECO:0000250|UniProtKB:Q01466};
DE   Flags: Precursor;
GN   Name=mreC {ECO:0000250|UniProtKB:Q01466};
OS   Geobacillus stearothermophilus (Bacillus stearothermophilus).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus.
OX   NCBI_TaxID=1422;
RN   [1] {ECO:0000305, ECO:0000312|PIR:JC4595}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=HA19;
RX   PubMed=9063975; DOI=10.1271/bbb.60.271;
RA   Kubo M., Pierro D.J., Mochizuki Y., Kojima T., Yamazaki T., Satoh S.,
RA   Takizawa N., Kiyohara H.;
RT   "Bacillus stearothermophilus cell shape determinant gene, mreC and mreD,
RT   and their stimulation of protease production in Bacillus subtilis.";
RL   Biosci. Biotechnol. Biochem. 60:271-276(1996).
CC   -!- FUNCTION: Involved in formation and maintenance of cell shape.
CC       Regulates protease expression and stimulates the neutral protease
CC       production in Bacilli together with MreD.
CC       {ECO:0000250|UniProtKB:Q01466, ECO:0000269|PubMed:9063975}.
CC   -!- SIMILARITY: Belongs to the MreC family. {ECO:0000305}.
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DR   PIR; JC4595; JC4595.
DR   AlphaFoldDB; P84480; -.
DR   BMRB; P84480; -.
DR   SMR; P84480; -.
DR   GO; GO:0016504; F:peptidase activator activity; IMP:UniProtKB.
DR   GO; GO:0010952; P:positive regulation of peptidase activity; IMP:UniProtKB.
DR   GO; GO:0008360; P:regulation of cell shape; ISS:UniProtKB.
DR   Gene3D; 2.40.10.340; -; 1.
DR   Gene3D; 2.40.10.350; -; 1.
DR   InterPro; IPR042177; Cell/Rod_1.
DR   InterPro; IPR042175; Cell/Rod_MreC_2.
DR   InterPro; IPR007221; MreC.
DR   PANTHER; PTHR34138; PTHR34138; 1.
DR   Pfam; PF04085; MreC; 1.
DR   PIRSF; PIRSF038471; MreC; 1.
DR   TIGRFAMs; TIGR00219; mreC; 1.
PE   3: Inferred from homology;
KW   Cell shape; Coiled coil; Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..290
FT                   /note="Cell shape-determining protein MreC"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000418057"
FT   COILED          58..111
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   290 AA;  32141 MW;  B9984D25BB414A5C CRC64;
     MPNKRLMLLL LCIIILVAMI GFSLKGGRNT TWPEKVIGDT TGVFQNIFHT PAEFFAGIFE
     NINDLKNTYK ENERLREKLD GQTQYEAKLQ ELEEENKSLR DELGHVKSIK DYKPILATVI
     ARSPDNWAKQ VTINKGTQQN VAKDMAVTNE KGALIGKIKS SGLNNFTSAV QLLSDTDRNN
     RVATKISGKK GSKGYGLIEG YDKEKKRLKM TIIERKDKQD VKKGDLIETS GTGGVFPEGL
     TIGEVTDIES DSYGLTKVAY VKPAADLTDL NNVIVVNRDV PTVDTEEEGS