ID   MRH_BPT4                Reviewed;         161 AA.
AC   P16007; Q9T0V9;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   19-DEC-2001, sequence version 3.
DT   23-FEB-2022, entry version 70.
DE   RecName: Full=RpoH-modulating protein;
GN   Name=mrh;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1692800; DOI=10.1016/0378-1119(90)90053-t;
RA   Frazier M.W., Mosig G.;
RT   "The bacteriophage T4 gene mrh whose product inhibits late T4 gene
RT   expression in an Escherichia coli rpoH (sigma 32) mutant.";
RL   Gene 88:7-14(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   FUNCTION.
RX   PubMed=9858714; DOI=10.1016/s0378-1119(98)00238-8;
RA   Mosig G., Colowick N.E., Pietz B.C.;
RT   "Several new bacteriophage T4 genes, mapped by sequencing deletion
RT   endpoints between genes 56 (dCTPase) and dda (a DNA-dependent ATPase-
RT   helicase) modulate transcription.";
RL   Gene 223:143-155(1998).
CC   -!- FUNCTION: Plays a role in transcriptional regulation of late T4 genes.
CC       Modulates the phosphorylation status of host heat shock sigma factor
CC       rpoH which is an initiation factor that promotes the attachment of host
CC       RNA polymerase to specific initiation sites.
CC       {ECO:0000269|PubMed:9858714}.
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DR   EMBL; M30001; AAB07796.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42612.1; -; Genomic_DNA.
DR   PIR; JH0136; ZMBPT4.
DR   PIR; T10137; T10137.
DR   RefSeq; NP_049641.1; NC_000866.4.
DR   GeneID; 1258731; -.
DR   KEGG; vg:1258731; -.
DR   Proteomes; UP000009087; Genome.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..161
FT                   /note="RpoH-modulating protein"
FT                   /id="PRO_0000164958"
SQ   SEQUENCE   161 AA;  18493 MW;  8A899DA7AB7038D0 CRC64;
     MEAILFEMSI NSISMAFVKD VPITVAVMID KRYDNNMYLV EDFISMPIPE DVEIKLKKIG
     IIETVQNSPF MAIQAFTKSN YIDVAEAYYN NKPLSFYSYD SIYDWKIDKG NKFIITDESA
     LSYFITSLWN NLNPNLLKIH KFDDAPTIVL GKTNESSEED A