ID   MRKC_KLEPN              Reviewed;         828 AA.
AC   P21647;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Outer membrane usher protein MrkC;
DE   Flags: Precursor;
GN   Name=mrkC;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IA565;
RX   PubMed=1670938; DOI=10.1128/jb.173.2.916-920.1991;
RA   Allen B.L., Gerlach G.-F., Clegg S.;
RT   "Nucleotide sequence and functions of mrk determinants necessary for
RT   expression of type 3 fimbriae in Klebsiella pneumoniae.";
RL   J. Bacteriol. 173:916-920(1991).
CC   -!- FUNCTION: Involved in the export and assembly of the type 3 fimbrial
CC       subunit (MrkA).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the fimbrial export usher family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M55912; AAA25095.1; -; Genomic_DNA.
DR   PIR; D39142; D39142.
DR   AlphaFoldDB; P21647; -.
DR   SMR; P21647; -.
DR   TCDB; 1.B.11.3.2; the outer membrane fimbrial usher porin (fup) family.
DR   PRIDE; P21647; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015473; F:fimbrial usher porin activity; IEA:InterPro.
DR   GO; GO:0009297; P:pilus assembly; IEA:InterPro.
DR   Gene3D; 2.60.40.2070; -; 1.
DR   Gene3D; 2.60.40.2610; -; 1.
DR   Gene3D; 3.10.20.410; -; 1.
DR   InterPro; IPR000015; Fimb_usher.
DR   InterPro; IPR018030; Fimbrial_membr_usher_CS.
DR   InterPro; IPR042186; FimD_plug_dom.
DR   InterPro; IPR025949; PapC-like_C.
DR   InterPro; IPR043142; PapC-like_C_sf.
DR   InterPro; IPR025885; PapC_N.
DR   InterPro; IPR037224; PapC_N_sf.
DR   PANTHER; PTHR30451; PTHR30451; 1.
DR   Pfam; PF13953; PapC_C; 1.
DR   Pfam; PF13954; PapC_N; 1.
DR   Pfam; PF00577; Usher; 1.
DR   SUPFAM; SSF141729; SSF141729; 1.
DR   PROSITE; PS01151; FIMBRIAL_USHER; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Disulfide bond; Fimbrium biogenesis; Membrane; Signal;
KW   Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..828
FT                   /note="Outer membrane usher protein MrkC"
FT                   /id="PRO_0000009321"
FT   DISULFID        813..827
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   828 AA;  91049 MW;  B30EDF5798249FC9 CRC64;
     MKQRSICPGR LSTAIAVALC CFPPFSSGQE SPGTIYQFND GFIVGSREKV DPSRFSTSAI
     SEGVYSLDVY TNGEWKGRYD LKITAGKDGK MGVCYTKAML MQYGISPEKL NPQLSEKEGF
     CGRLQEWRHE DNVKDTLIQS SLRLDIAVPQ IYEDQRLKNF VSPQFWDKGV AALNLGWMAN
     AWNSHISSAN GSDNSSAYLG VNAGLSWDGW LLKHIGNLNW QQQQGKAHWN SNQTYLQRPI
     PQINSIVSGG QIFTNGEFFD TIGLRGVNLA TDDNMFPDGM RSYAPEIRDV AQSNALATVR
     QGSNIIYQTT VPPGPFTLQD VYPSGYGSDL EVSVKEGDGS VEVFSVPYAS VAQLLRPGMT
     RYALSAGKVD DSSLRNKPML YQGTWQHGLN NLFTGYTGVT GFDDYQAFLL GTGMNTGIGA
     LSFDVTHTRL KSDTLDEHGQ SYRATFNRMF TETQTSIVLA AYRYSTKGYY NLNDALYAVD
     QEKNYNSNYT VWRQKNGMTF TVNQNLPDGW GGFYLCGRVA DYWNRSGTEK QYQFSYNNMY
     GRLSWSVDAQ RVYTPDSSGH RRDDRVSLNF SYPLWFGENR TANLTSNTAF NNSRFASSQI
     GVNGSLDSEN NLNYGVSTTT ATGRQHDVAL NGSYRTPWTT LNGSYSQGEG YRQSGVGASG
     TLIAHQHGVV FSPETGPTMA LIEAKDAAGV MLPGSPGTRI DSNGYAILPY LRPYRINSVE
     IDPKGSNDDV AFGSTVAQVV PWEGSVVKVS FDTTLQNNIT LRARQANGLP LPFAATIFGP
     SGKEIGVVGQ GSMMFISDAS APKATVKWSG GQCSVELSQE KTKETLCR