ID   MRN2_MEGVI              Reviewed;          63 AA.
AC   P83418;
DT   15-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   16-JAN-2004, sequence version 2.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Megourin-2;
OS   Megoura viciae (Vetch aphid).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; Aphidomorpha;
OC   Aphidoidea; Aphididae; Macrosiphini; Megoura.
OX   NCBI_TaxID=112273 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, FUNCTION, SUBUNIT, INDUCTION, AND MASS SPECTROMETRY.
RA   Bulet P., Charlet M., Chernish S., Hetru C.;
RL   Submitted (JUL-2002) to UniProtKB.
CC   -!- FUNCTION: Has antimicrobial activity against Gram-positive bacteria and
CC       fungi. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- SUBUNIT: Monomer. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- INDUCTION: By bacterial infection. {ECO:0000269|Ref.1, ECO:0000305}.
CC   -!- PTM: Contains four disulfide bonds.
CC   -!- MASS SPECTROMETRY: Mass=6943.35; Method=MALDI;
CC       Evidence={ECO:0000269|Ref.1};
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DR   AlphaFoldDB; P83418; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR035171; Megourin.
DR   Pfam; PF17560; Megourin; 1.
PE   1: Evidence at protein level;
KW   Antibiotic; Antimicrobial; Direct protein sequencing; Disulfide bond;
KW   Fungicide; Immunity; Innate immunity; Secreted.
FT   CHAIN           1..63
FT                   /note="Megourin-2"
FT                   /id="PRO_0000096577"
SQ   SEQUENCE   63 AA;  6952 MW;  313A4C1A7424D320 CRC64;
     YLDVNQIASY LLCLGQGAVF NGRKTCQIGC RAACQQPGCG GYKECEQIPN IRLHKYRCHC
     NSG