MRNC_BREBN
ID MRNC_BREBN Reviewed; 134 AA.
AC C0ZIF8;
DT 21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT 26-MAY-2009, sequence version 1.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=Mini-ribonuclease 3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-RNase 3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01468};
DE AltName: Full=Mini-RNase III {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-III {ECO:0000255|HAMAP-Rule:MF_01468};
GN Name=mrnC {ECO:0000255|HAMAP-Rule:MF_01468}; OrderedLocusNames=BBR47_01990;
OS Brevibacillus brevis (strain 47 / JCM 6285 / NBRC 100599).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX NCBI_TaxID=358681;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=47 / JCM 6285 / NBRC 100599;
RA Hosoyama A., Yamada R., Hongo Y., Terui Y., Ankai A., Masuyama W.,
RA Sekiguchi M., Takeda T., Asano K., Ohji S., Ichikawa N., Narita S.,
RA Aoki N., Miura H., Matsushita S., Sekigawa T., Yamagata H., Yoshikawa H.,
RA Udaka S., Tanikawa S., Fujita N.;
RT "Brevibacillus brevis strain 47, complete genome.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in correct processing of both the 5' and 3' ends of
CC 23S rRNA precursor. Processes 30S rRNA precursor transcript even in
CC absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller
CC rRNA precursors. {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01468};
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000255|HAMAP-
CC Rule:MF_01468}.
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DR EMBL; AP008955; BAH41176.1; -; Genomic_DNA.
DR RefSeq; WP_007716204.1; NC_012491.1.
DR AlphaFoldDB; C0ZIF8; -.
DR SMR; C0ZIF8; -.
DR STRING; 358681.BBR47_01990; -.
DR EnsemblBacteria; BAH41176; BAH41176; BBR47_01990.
DR GeneID; 61030474; -.
DR KEGG; bbe:BBR47_01990; -.
DR eggNOG; COG1939; Bacteria.
DR HOGENOM; CLU_091169_2_1_9; -.
DR OMA; AYMGDAI; -.
DR OrthoDB; 1939897at2; -.
DR Proteomes; UP000001877; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR CDD; cd00593; RIBOc; 1.
DR Gene3D; 1.10.1520.10; -; 1.
DR HAMAP; MF_01468; RNase_Mini_III; 1.
DR InterPro; IPR008226; Mini3_fam.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR Pfam; PF00636; Ribonuclease_3; 1.
DR PIRSF; PIRSF005520; UCP005520; 1.
DR SMART; SM00535; RIBOc; 1.
DR SUPFAM; SSF69065; SSF69065; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Endonuclease; Hydrolase; Magnesium; Nuclease;
KW Reference proteome; Ribosome biogenesis; RNA-binding; rRNA processing;
KW rRNA-binding.
FT CHAIN 1..134
FT /note="Mini-ribonuclease 3"
FT /id="PRO_0000415981"
FT ACT_SITE 23
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01468"
SQ SEQUENCE 134 AA; 14838 MW; 67F027DDE0D326E8 CRC64;
MQKEELTRDP NLTNPLVLAF LGDATYSHCV RYHLIAKGLV KPNQLHKAAN RYVSAKAQAN
VLLTLMPTLP EEELNVVKRG RNAKSGSSAK NADIIDYRHA TAFEALIGYL YLSGKEERIA
EIVQQAFAIV EGES
