MRNC_LACLA
ID MRNC_LACLA Reviewed; 133 AA.
AC Q9CEJ1;
DT 21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Mini-ribonuclease 3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-RNase 3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01468};
DE AltName: Full=Mini-RNase III {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-III {ECO:0000255|HAMAP-Rule:MF_01468};
GN Name=mrnC {ECO:0000255|HAMAP-Rule:MF_01468}; OrderedLocusNames=LL1850;
GN ORFNames=L101219;
OS Lactococcus lactis subsp. lactis (strain IL1403) (Streptococcus lactis).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=272623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IL1403;
RX PubMed=11337471; DOI=10.1101/gr.gr-1697r;
RA Bolotin A., Wincker P., Mauger S., Jaillon O., Malarme K., Weissenbach J.,
RA Ehrlich S.D., Sorokin A.;
RT "The complete genome sequence of the lactic acid bacterium Lactococcus
RT lactis ssp. lactis IL1403.";
RL Genome Res. 11:731-753(2001).
CC -!- FUNCTION: Involved in correct processing of both the 5' and 3' ends of
CC 23S rRNA precursor. Processes 30S rRNA precursor transcript even in
CC absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller
CC rRNA precursors. {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01468};
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000255|HAMAP-
CC Rule:MF_01468}.
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DR EMBL; AE005176; AAK05948.1; -; Genomic_DNA.
DR PIR; B86856; B86856.
DR RefSeq; NP_268007.1; NC_002662.1.
DR RefSeq; WP_003132362.1; NC_002662.1.
DR AlphaFoldDB; Q9CEJ1; -.
DR SMR; Q9CEJ1; -.
DR STRING; 272623.L101219; -.
DR PaxDb; Q9CEJ1; -.
DR EnsemblBacteria; AAK05948; AAK05948; L101219.
DR KEGG; lla:L101219; -.
DR PATRIC; fig|272623.7.peg.1982; -.
DR eggNOG; COG1939; Bacteria.
DR HOGENOM; CLU_091169_2_0_9; -.
DR OMA; AYMGDAI; -.
DR Proteomes; UP000002196; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1520.10; -; 1.
DR HAMAP; MF_01468; RNase_Mini_III; 1.
DR InterPro; IPR008226; Mini3_fam.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR Pfam; PF00636; Ribonuclease_3; 1.
DR PIRSF; PIRSF005520; UCP005520; 1.
DR SUPFAM; SSF69065; SSF69065; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Endonuclease; Hydrolase; Magnesium; Nuclease;
KW Reference proteome; Ribosome biogenesis; RNA-binding; rRNA processing;
KW rRNA-binding.
FT CHAIN 1..133
FT /note="Mini-ribonuclease 3"
FT /id="PRO_0000415987"
FT ACT_SITE 19
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01468"
SQ SEQUENCE 133 AA; 15128 MW; 8DC578EC928BFFCD CRC64;
MNKQQAELLN GIALAYIGDA IYEVFVREYL LDKGLTKPAM LQKNATKFVS AKAQAKIISA
MDEVDFLTEY ELTYFKRGRN AHSKTTAKNT DVVTYRISTG FEAVVGILHL TQQKERLQEF
WDFSLKTIEA DLV
