MRNC_MOOTA
ID MRNC_MOOTA Reviewed; 127 AA.
AC Q2RFM4;
DT 21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 25-MAY-2022, entry version 76.
DE RecName: Full=Mini-ribonuclease 3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-RNase 3 {ECO:0000255|HAMAP-Rule:MF_01468};
DE EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01468};
DE AltName: Full=Mini-RNase III {ECO:0000255|HAMAP-Rule:MF_01468};
DE Short=Mini-III {ECO:0000255|HAMAP-Rule:MF_01468};
GN Name=mrnC {ECO:0000255|HAMAP-Rule:MF_01468}; OrderedLocusNames=Moth_2483;
OS Moorella thermoacetica (strain ATCC 39073 / JCM 9320).
OC Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Moorella group; Moorella.
OX NCBI_TaxID=264732;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39073 / JCM 9320;
RX PubMed=18631365; DOI=10.1111/j.1462-2920.2008.01679.x;
RA Pierce E., Xie G., Barabote R.D., Saunders E., Han C.S., Detter J.C.,
RA Richardson P., Brettin T.S., Das A., Ljungdahl L.G., Ragsdale S.W.;
RT "The complete genome sequence of Moorella thermoacetica (f. Clostridium
RT thermoaceticum).";
RL Environ. Microbiol. 10:2550-2573(2008).
CC -!- FUNCTION: Involved in correct processing of both the 5' and 3' ends of
CC 23S rRNA precursor. Processes 30S rRNA precursor transcript even in
CC absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller
CC rRNA precursors. {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01468};
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01468}.
CC -!- SIMILARITY: Belongs to the MrnC RNase family. {ECO:0000255|HAMAP-
CC Rule:MF_01468}.
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DR EMBL; CP000232; ABC20765.1; -; Genomic_DNA.
DR RefSeq; YP_431308.1; NC_007644.1.
DR AlphaFoldDB; Q2RFM4; -.
DR SMR; Q2RFM4; -.
DR STRING; 264732.Moth_2483; -.
DR EnsemblBacteria; ABC20765; ABC20765; Moth_2483.
DR KEGG; mta:Moth_2483; -.
DR PATRIC; fig|264732.11.peg.2703; -.
DR eggNOG; COG1939; Bacteria.
DR HOGENOM; CLU_091169_2_1_9; -.
DR OMA; AYMGDAI; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1520.10; -; 1.
DR HAMAP; MF_01468; RNase_Mini_III; 1.
DR InterPro; IPR008226; Mini3_fam.
DR InterPro; IPR000999; RNase_III_dom.
DR InterPro; IPR036389; RNase_III_sf.
DR Pfam; PF00636; Ribonuclease_3; 1.
DR PIRSF; PIRSF005520; UCP005520; 1.
DR SUPFAM; SSF69065; SSF69065; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Endonuclease; Hydrolase; Magnesium; Nuclease;
KW Ribosome biogenesis; RNA-binding; rRNA processing; rRNA-binding.
FT CHAIN 1..127
FT /note="Mini-ribonuclease 3"
FT /id="PRO_0000415990"
FT ACT_SITE 17
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01468"
SQ SEQUENCE 127 AA; 14157 MW; 43306E66E802EF0D CRC64;
MDFVANLSPL ALAYVGDAVY ELLVRAHLVG RGPAKPEQLH REALKYVRAT AQARVVPALE
EYLTPAEKDI LRRGRNARPG HLPRTAAPAE YHSSTALESL LGYLYLQGDW ARVEELAHLI
FKLAEQD
