ID   MROH1_BOVIN             Reviewed;        1652 AA.
AC   A7E2Y6; Q7YR93;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Maestro heat-like repeat-containing protein family member 1;
DE   AltName: Full=HEAT repeat-containing protein 7A;
GN   Name=MROH1; Synonyms=HEATR7A;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hypothalamus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 934-1102.
RX   PubMed=14667821; DOI=10.1016/s0888-7543(03)00238-6;
RA   Winter A., Alzinger A., Fries R.;
RT   "Assessment of the gene content of the chromosomal regions flanking bovine
RT   DGAT1.";
RL   Genomics 83:172-180(2004).
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DR   EMBL; BC151617; AAI51618.1; -; mRNA.
DR   EMBL; AJ518965; CAD58802.1; -; Genomic_DNA.
DR   RefSeq; NP_001095488.1; NM_001102018.1.
DR   AlphaFoldDB; A7E2Y6; -.
DR   STRING; 9913.ENSBTAP00000037251; -.
DR   PaxDb; A7E2Y6; -.
DR   PRIDE; A7E2Y6; -.
DR   GeneID; 515055; -.
DR   KEGG; bta:515055; -.
DR   CTD; 727957; -.
DR   eggNOG; KOG2032; Eukaryota.
DR   InParanoid; A7E2Y6; -.
DR   OrthoDB; 31329at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR045206; Maestro_heat-like_prot.
DR   PANTHER; PTHR23120; PTHR23120; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   SUPFAM; SSF48371; SSF48371; 2.
DR   PROSITE; PS50077; HEAT_REPEAT; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat.
FT   CHAIN           1..1652
FT                   /note="Maestro heat-like repeat-containing protein family
FT                   member 1"
FT                   /id="PRO_0000329401"
FT   REPEAT          3..41
FT                   /note="HEAT 1"
FT   REPEAT          260..300
FT                   /note="HEAT 2"
FT   REPEAT          344..382
FT                   /note="HEAT 3"
FT   REPEAT          385..423
FT                   /note="HEAT 4"
FT   REPEAT          1369..1407
FT                   /note="HEAT 5"
FT   REPEAT          1410..1448
FT                   /note="HEAT 6"
FT   REPEAT          1616..1652
FT                   /note="HEAT 7"
FT   CONFLICT        1061
FT                   /note="H -> Q (in Ref. 2; CAD58802)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1652 AA;  182135 MW;  15B77F71C3B6CB3D CRC64;
     MSETYAKRLS AILLDAVTDK DPQMQEQVCG ALCDFGESKP AEVLSACEEH LRLHEKLAHP
     YRTIILRAME IVVSNHISEL DKDTARAIIL LASNEMTKVK ELVSDWQQAA SSVLVAVGRR
     FISSVMEELL SKFQPGLLPH PCTVHTLASL SVSNVFGVVP FLTSILSTML PMLGAAKHDS
     MKVVFCCALQ RFSESILEYL ANLDQAPDPT VRKDAFASDI FGAYDILFHQ WLQSGGAKLR
     LAVVEALGPM SHLLPSEKLE EQLPKLLPRV LAFYKKHTET VHVSKSLGQI LEAAVSVGSR
     TLDIHLNSLL AALHAQICVP VESSSPLVMS NQKEVLRCFT VLACCSPDRL LAFLLPKLDT
     SNERTRVGTL QVLRHVINAA AAQMEVKKPV ILSSMKLPLL DTNNKVKRAV VQVVSAMAHH
     GYLEQPGGKA MVEYIVQQCA LPPEAEIQKL GADSEALAAD SVRAISVSTL YLVSTTVDRM
     GEVLWPYLLE FLVPIRFTRA LSPLCRSLVH LAQKRQEAGA HAPLIQYNGN VHLPSPYAIT
     TRLLAVSSHP YVGDGRGAAS LRLLNVLHQD IHPALGQRWV TAIPLLLEHL DEYSEETLSQ
     KEWEEKLLVF LRDSLAVVSD NTWVCHLTLE MCKQLPNYNG TPLEKNFLYK CVGTTLGAAS
     SKVVRKHLRE LLETARYQEE REHEGLACCF GICAISHLDD TLAQLDDFVK SDVLRKSAGI
     FNLFKNRSES EANKVRSALI LCYGHVAAGA PRELLLARVE ADLFWNMSEC FSTKVLGIKV
     ETQDPALRLS LVQSVCMATQ AICSSAHSSS FHLSRKAELV AQMVEFIRAE PPDSLKTPIW
     KKAMLACTYL VTLEPALEEQ VQADLIHSCL HRVMAVLPEP EEGDSPQEVS AAPTVGGDPQ
     ESLYLDTVQV LKDLLTSLLL WNMTPLGLQV MLEHLSPWIK SPRGHERVRA VGLSACLLQF
     FLQHLQISAL VPFHNLGLLI GLFSPRCADL WPATRREAVS CIHSLLYLQL TCVGFSRDYQ
     DDVAEQLLSL KDGLVHPDPA ILFHTCHSIA QLIAKRLPPD HLINLLLTLF ESLGDPDKNC
     SRAASVMINC LLKERGNMLQ EKVPEIVSVL RSKLQETQEE HILQAAQHSV FALATHHCAS
     VVSNLLGSPL PFDSHTCTLW RALALEPGLA AQVLGLLLEK ISKDVLFEES QAFLLSSTPD
     RVATLLPLAA TCALHEVASA PASGPAVLEL YPQLFVALLL RVSCTVGVQP PRQLQAKERR
     SASSGLASRS LEPCSSAVDA LQAVLVRGGN EDVVQCMELD GGWQLLRTSA GHEEGVTRLA
     SAMAKFAGPR LPLVMKLLFT TQSSMYEVQR VTSTAFLAEL LSSNVVNDLM LLESLLYNLM
     ARQKDTSARV RRLVLHGLAN ITLGSPDKVQ THSPQLLTAM IGGLDDGDDP HSLVALEAMV
     GLARLMDLVD AWDLHAVLLH IAVRIRPFFD SERMELRSVS IGLFGHLNKA CRGDCKDVFL
     EQVVGGLVPL LLHLRDPHAP VVTACRFALR MCGPNLECEE LAAVFQRHLQ EGHDLHFGEF
     LNTTCKHLMR HFPDLLGRLL STSLFYYKSS WEDVRAAAPM LTGFLVLHME AEQRPQVDLE
     QLLTALQLLL KDPALKVRLK AVKTLGRLVK FA