ID   MRPA_PROMH              Reviewed;         175 AA.
AC   Q03011; B4EUJ9;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Major MR/P fimbria protein;
DE   Flags: Precursor;
GN   Name=mrpA; OrderedLocusNames=PMI0263;
OS   Proteus mirabilis (strain HI4320).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Morganellaceae; Proteus.
OX   NCBI_TaxID=529507;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 24-43.
RX   PubMed=8093447; DOI=10.1128/jb.175.2.457-464.1993;
RA   Bahrani F.K., Mobley H.L.T.;
RT   "Proteus mirabilis MR/P fimbriae: molecular cloning, expression, and
RT   nucleotide sequence of the major fimbrial subunit gene.";
RL   J. Bacteriol. 175:457-464(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7910820; DOI=10.1128/jb.176.11.3412-3419.1994;
RA   Bahrani F.K., Mobley H.L.T.;
RT   "Proteus mirabilis MR/P fimbrial operon: genetic organization, nucleotide
RT   sequence, and conditions for expression.";
RL   J. Bacteriol. 176:3412-3419(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HI4320;
RX   PubMed=18375554; DOI=10.1128/jb.01981-07;
RA   Pearson M.M., Sebaihia M., Churcher C., Quail M.A., Seshasayee A.S.,
RA   Luscombe N.M., Abdellah Z., Arrosmith C., Atkin B., Chillingworth T.,
RA   Hauser H., Jagels K., Moule S., Mungall K., Norbertczak H.,
RA   Rabbinowitsch E., Walker D., Whithead S., Thomson N.R., Rather P.N.,
RA   Parkhill J., Mobley H.L.T.;
RT   "Complete genome sequence of uropathogenic Proteus mirabilis, a master of
RT   both adherence and motility.";
RL   J. Bacteriol. 190:4027-4037(2008).
CC   -!- FUNCTION: Major structural component of mannose-resistant/proteus-like
CC       fimbriae of P.mirabilis.
CC   -!- SUBCELLULAR LOCATION: Fimbrium.
CC   -!- SIMILARITY: Belongs to the fimbrial protein family. {ECO:0000305}.
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DR   EMBL; Z18753; CAA79244.1; -; Genomic_DNA.
DR   EMBL; Z32686; CAA83633.1; -; Genomic_DNA.
DR   EMBL; AM942759; CAR40720.1; -; Genomic_DNA.
DR   PIR; A40643; A40643.
DR   RefSeq; WP_004247325.1; NC_010554.1.
DR   AlphaFoldDB; Q03011; -.
DR   SMR; Q03011; -.
DR   STRING; 529507.PMI0263; -.
DR   DNASU; 6803219; -.
DR   EnsemblBacteria; CAR40720; CAR40720; PMI0263.
DR   GeneID; 6803219; -.
DR   KEGG; pmr:PMI0263; -.
DR   eggNOG; COG3539; Bacteria.
DR   HOGENOM; CLU_088965_3_1_6; -.
DR   OMA; QDCNFNT; -.
DR   Proteomes; UP000008319; Chromosome.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR000259; Adhesion_dom_fimbrial.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   Pfam; PF00419; Fimbrial; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Fimbrium; Reference proteome;
KW   Signal.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000269|PubMed:8093447"
FT   CHAIN           24..175
FT                   /note="Major MR/P fimbria protein"
FT                   /id="PRO_0000009231"
FT   DISULFID        42..81
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   175 AA;  17910 MW;  6D0441263646B6BA CRC64;
     MKLNKLALVL GLGLSVVAGS ALAADQGHGT VKFVGSIIDA PCSITPDTEN QTVPLGQIST
     AALKDGGRSN SRDFKISLEN CTTETYKTVQ TTFTGSEATE VLEGSLGIEG IAKNAAVVIT
     DAGGKQIKLG TPSAAQNLRD GNNDLNFAAY LQGSASEAAV PGDFTAIATF ALTYQ