ID   MRS2A_ORYSI             Reviewed;         474 AA.
AC   B8APK3;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Magnesium transporter MRS2-A, chloroplastic;
DE   Flags: Precursor;
GN   Name=MRS2-A; ORFNames=OsI_13056;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC       magnesium in chloroplast. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Plastid. Plastid, chloroplast membrane
CC       {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC       1.A.35.5) family. {ECO:0000305}.
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DR   EMBL; CM000128; EEC75953.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8APK3; -.
DR   SMR; B8APK3; -.
DR   STRING; 39946.B8APK3; -.
DR   EnsemblPlants; BGIOSGA013344-TA; BGIOSGA013344-PA; BGIOSGA013344.
DR   Gramene; BGIOSGA013344-TA; BGIOSGA013344-PA; BGIOSGA013344.
DR   HOGENOM; CLU_025144_0_0_1; -.
DR   OMA; QVGAFCV; -.
DR   Proteomes; UP000007015; Chromosome 3.
DR   GO; GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:EnsemblPlants.
DR   GO; GO:0010960; P:magnesium ion homeostasis; IEA:EnsemblPlants.
DR   GO; GO:0010117; P:photoprotection; IEA:EnsemblPlants.
DR   GO; GO:0010027; P:thylakoid membrane organization; IEA:EnsemblPlants.
DR   CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   InterPro; IPR039204; MRS2-like.
DR   PANTHER; PTHR13890; PTHR13890; 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF144083; SSF144083; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Ion transport; Magnesium; Membrane; Plastid;
KW   Reference proteome; Transit peptide; Transmembrane; Transmembrane helix;
KW   Transport.
FT   TRANSIT         1..55
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           56..474
FT                   /note="Magnesium transporter MRS2-A, chloroplastic"
FT                   /id="PRO_0000394266"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        444..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          79..129
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           432..434
FT                   /note="Required for magnesium transport activity"
FT   COMPBIAS        100..119
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   474 AA;  51892 MW;  02213D1F79FEDF3B CRC64;
     MASVSSSPSY SSQAAVLLLL HQPPHQHGHG GACLRYRGSQ SQGRGNAVAT SLGLSAAGRG
     GAGGLLLLPP LPALRAAEGK DGRAVTKDEE EEAAAAAVEE EGEVEVRREE DKPGDDGSRE
     AAARGSGSGR FSADYISLGI REPVYEVIEV KSNGRMSTKK ISRRQLLKSS GLRLRDTRSV
     DPSLWLMNSM PSLLVREQAI LVNLGSLRAI AMHERVLIFN YNSPGGKAFL DSLLPRLNPR
     NINGGPAMPF QLEVVEAALL SRIQRLERRL MRIEPRVGAL LEVLPNRLTA DVLEQLRLSK
     QALVELGSRA GDLKQMLIDL LDDPHEIRRI CIMGRNCTLD KLSDNMECSV PLEKQIAEEE
     EEEIEMLLEN YLQRCESIHG QAERLLDSAR EMEDSIAVNL SSRRLEVSRV ELLLQVGTFC
     VAIGALIAGI FGMNLKSYLE TNAWAFWATT GGIVVGAVAG FFIMYSYLKT RKIL