ID   MRS2B_ORYSI             Reviewed;         436 AA.
AC   A2YFN7;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Magnesium transporter MRS2-B;
GN   Name=MRS2-B; ORFNames=OsI_23924;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC       magnesium. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC       1.A.35.5) family. {ECO:0000305}.
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DR   EMBL; CM000131; EAZ01898.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2YFN7; -.
DR   SMR; A2YFN7; -.
DR   STRING; 39946.A2YFN7; -.
DR   iPTMnet; A2YFN7; -.
DR   PRIDE; A2YFN7; -.
DR   EnsemblPlants; BGIOSGA020774-TA; BGIOSGA020774-PA; BGIOSGA020774.
DR   Gramene; BGIOSGA020774-TA; BGIOSGA020774-PA; BGIOSGA020774.
DR   HOGENOM; CLU_034694_1_1_1; -.
DR   OMA; RNFDNVF; -.
DR   Proteomes; UP000007015; Chromosome 6.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR039204; MRS2-like.
DR   PANTHER; PTHR13890; PTHR13890; 1.
DR   SUPFAM; SSF144083; SSF144083; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Ion transport; Magnesium; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..436
FT                   /note="Magnesium transporter MRS2-B"
FT                   /id="PRO_0000394268"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        408..428
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          176..242
FT                   /evidence="ECO:0000255"
FT   MOTIF           392..394
FT                   /note="Required for magnesium transport activity"
SQ   SEQUENCE   436 AA;  48473 MW;  EFC5CC2EC0EAD785 CRC64;
     MSAAAASSAA GDSAKQPLLH HQRGNPPHVA SVSSPSLPSA PPGALAGGRR FPGGLDVPNL
     KKRGGGTRSW IRVEAATASV QTLEVDKATM MRRCELPARD LRLLDPLFVY PSTILGRERA
     IVVNLEQIRC VITADEVLLL NSLDSYVLQY AAELQRRLLQ RAEGDELPFE FRALELALEA
     ACSFLDAQAA ELEIEAYPLL DELTSKISTL NLERVRRLKS RLVALTRRVQ KVRDEIEQLM
     DDDGDMAEMY LSEKKLRTEA SFYGDQSMLG YNSVGDGTSF SAPVSPVSSP TESRKLEKAF
     SLCRSRHDSV KSSDNTATEH IQELEMLLEA YFVVIDSTLN KLTSLKEYID DTEDFINIQL
     DNVRNQLIQF ELLLTTATFV VAIFGVVAGI FGMNFETSVF SIQNAFQWVL IITGVIGAFI
     FCGFLWFFKY KRLMPL