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MRS2D_ORYSI
ID   MRS2D_ORYSI             Reviewed;         434 AA.
AC   Q01JR9; A2XTK1;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=Putative magnesium transporter MRS2-D;
GN   Name=MRS2-D; ORFNames=OsI_15936, OSIGBa0160I14.4;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Guang-Lu-Ai No.4;
RX   PubMed=12447439; DOI=10.1038/nature01183;
RA   Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA   Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA   Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA   Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA   Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA   Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA   Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA   Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA   Li J., Hong G., Xue Y., Han B.;
RT   "Sequence and analysis of rice chromosome 4.";
RL   Nature 420:316-320(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Putative magnesium transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC       1.A.35.5) family. {ECO:0000305}.
CC   -!- CAUTION: Lacks the GMN motif, which is a conserved feature of the
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAY94161.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CR855163; CAH67006.1; -; Genomic_DNA.
DR   EMBL; CM000129; EAY94161.1; ALT_SEQ; Genomic_DNA.
DR   AlphaFoldDB; Q01JR9; -.
DR   SMR; Q01JR9; -.
DR   STRING; 39946.Q01JR9; -.
DR   HOGENOM; CLU_034694_0_0_1; -.
DR   Proteomes; UP000007015; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR   InterPro; IPR039204; MRS2-like.
DR   PANTHER; PTHR13890; PTHR13890; 1.
PE   3: Inferred from homology;
KW   Ion transport; Magnesium; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..434
FT                   /note="Putative magnesium transporter MRS2-D"
FT                   /id="PRO_0000394272"
FT   TRANSMEM        367..387
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        405..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          279..311
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        279..296
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        23
FT                   /note="P -> A (in Ref. 2; EAY94161)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        154
FT                   /note="Q -> P (in Ref. 2; EAY94161)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        216
FT                   /note="T -> S (in Ref. 2; EAY94161)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   434 AA;  45581 MW;  2214740DE5BB4E0F CRC64;
     MAARRRHVAA GAGAPAPAAG EWPAVTAGGG AAWALSPVEE VGTKQELMRR TGLPPRDLRA
     LDPALSSAAS ASSCRPSAIT GRDRAVVVNL DRARAVITAS EVLVPSPRDP AVAPLVRELR
     ARLALAASPT PAPSPSPPQH GMAVGMDGSI SPSQASRGGE EAAGNGKDGE ALGGGDKALP
     FEFRALEVCL EFACKSLEHE TCTLEKEAYP ALDELTSKVS TLNLERVRQI KSRLVAISGK
     VQKVRDELEH LLDDDMDMAA LHLTEKLAYQ SSRFDIDKEA SELEDHSSRD EEGVEGGGGG
     DGDDETIAGG GSFSPNTDEL EILLESYFVQ IDGTLNSLST LREYVEDTED YINMMLDEKQ
     NQLLQMGILL STGTLVSSCA IAVTGVFGIN VHISLYDSPA SSAAFPCAAA GIVAGSLALY
     LAALLCYKRA GILQ
 
 
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