ID   MRS2F_ORYSI             Reviewed;         444 AA.
AC   A2WY50;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Magnesium transporter MRS2-F;
GN   Name=MRS2-F; ORFNames=OsI_04855;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC       magnesium. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC       1.A.35.5) family. {ECO:0000305}.
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DR   EMBL; CM000126; EAY76896.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2WY50; -.
DR   SMR; A2WY50; -.
DR   EnsemblPlants; BGIOSGA000291-TA; BGIOSGA000291-PA; BGIOSGA000291.
DR   Gramene; BGIOSGA000291-TA; BGIOSGA000291-PA; BGIOSGA000291.
DR   HOGENOM; CLU_034694_0_0_1; -.
DR   OMA; WMVVPAS; -.
DR   Proteomes; UP000007015; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR   InterPro; IPR039204; MRS2-like.
DR   PANTHER; PTHR13890; PTHR13890; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Ion transport; Magnesium; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..444
FT                   /note="Magnesium transporter MRS2-F"
FT                   /id="PRO_0000394276"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        415..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          128..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          195..258
FT                   /evidence="ECO:0000255"
FT   MOTIF           391..393
FT                   /note="Required for magnesium transport activity"
SQ   SEQUENCE   444 AA;  48356 MW;  4FED4476772D1CE6 CRC64;
     MRPSAAAGGG GGGGGRRKAA AAAAAASREW LVVPASGQAR VEEAGKHAVM ARTGLPARDL
     RVLDPLLSYP STILGRERAI VVNLERVKAV ITAAEVLLPN SKDPAFASFV CDLQARVLAS
     SSDQAAEFTD MEGESSAVTS PFPALTSTTP NELEMTNKNS NVVGGMTHSN SMPTLTAAKD
     GNTKVLPFEF RALEVCLESA CRSLEEETST LEQEAYPALD ELTSKISTLN LERVRQIKSR
     LVAISGRVQK VRDELEHLLD DEMDMAEMYL TEKLTRQEIS ETSSRVEVDD PSQLEVDRDE
     DYRSEADVSN GTFIGYKPHI EELEMLLEAY FVQIDGTLNK LSHLREYVDD TEDYINIMLD
     DKQNQLLQMG VMLSTATVVI TAGVAVVGLF GMNIGISLYA DPTNEEEKRA SNMKFWETTL
     GTIAGCTVMY IVAMGWGKRS GLLQ