MRS2F_ORYSJ
ID MRS2F_ORYSJ Reviewed; 444 AA.
AC Q8L4S2; A0A0P0VBV1; Q84VA9;
DT 18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Magnesium transporter MRS2-F;
GN Name=MRS2-F; OrderedLocusNames=Os01g0908500, LOC_Os01g68040;
GN ORFNames=B1417F08.35, OsJ_04478, P0456E05.8, P0497A05.17;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 120-277, AND INTERACTION WITH CYCB2-2.
RC STRAIN=cv. Nipponbare;
RX PubMed=14750518; DOI=10.1023/b:plan.0000007001.30865.0f;
RA Cooper B., Hutchison D., Park S., Guimil S., Luginbuehl P., Ellero C.,
RA Goff S.A., Glazebrook J.;
RT "Identification of rice (Oryza sativa) proteins linked to the cyclin-
RT mediated regulation of the cell cycle.";
RL Plant Mol. Biol. 53:273-279(2003).
RN [7]
RP GENE FAMILY.
RX PubMed=19966073; DOI=10.1105/tpc.109.070557;
RA Gebert M., Meschenmoser K., Svidova S., Weghuber J., Schweyen R.,
RA Eifler K., Lenz H., Weyand K., Knoop V.;
RT "A root-expressed magnesium transporter of the MRS2/MGT gene family in
RT Arabidopsis thaliana allows for growth in low-Mg2+ environments.";
RL Plant Cell 21:4018-4030(2009).
CC -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC magnesium. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with CYCB2-2. {ECO:0000269|PubMed:14750518}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC 1.A.35.5) family. {ECO:0000305}.
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DR EMBL; AP003380; BAB92573.1; -; Genomic_DNA.
DR EMBL; AP003416; BAB92606.1; -; Genomic_DNA.
DR EMBL; AP006531; BAD82756.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS75810.1; -; Genomic_DNA.
DR EMBL; CM000138; EAZ14556.1; -; Genomic_DNA.
DR EMBL; AK120875; BAH00210.1; -; mRNA.
DR EMBL; AY224580; AAO72700.1; -; mRNA.
DR RefSeq; XP_015616461.1; XM_015760975.1.
DR AlphaFoldDB; Q8L4S2; -.
DR SMR; Q8L4S2; -.
DR STRING; 4530.OS01T0908500-01; -.
DR PaxDb; Q8L4S2; -.
DR PRIDE; Q8L4S2; -.
DR EnsemblPlants; Os01t0908500-01; Os01t0908500-01; Os01g0908500.
DR GeneID; 4324988; -.
DR Gramene; Os01t0908500-01; Os01t0908500-01; Os01g0908500.
DR KEGG; osa:4324988; -.
DR eggNOG; KOG2662; Eukaryota.
DR HOGENOM; CLU_034694_0_0_1; -.
DR InParanoid; Q8L4S2; -.
DR OMA; WMVVPAS; -.
DR OrthoDB; 1363588at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR ExpressionAtlas; Q8L4S2; baseline and differential.
DR Genevisible; Q8L4S2; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015693; P:magnesium ion transport; IBA:GO_Central.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890; PTHR13890; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Ion transport; Magnesium; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..444
FT /note="Magnesium transporter MRS2-F"
FT /id="PRO_0000394275"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 415..435
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 128..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 195..258
FT /evidence="ECO:0000255"
FT MOTIF 391..393
FT /note="Required for magnesium transport activity"
SQ SEQUENCE 444 AA; 48356 MW; 4FED4476772D1CE6 CRC64;
MRPSAAAGGG GGGGGRRKAA AAAAAASREW LVVPASGQAR VEEAGKHAVM ARTGLPARDL
RVLDPLLSYP STILGRERAI VVNLERVKAV ITAAEVLLPN SKDPAFASFV CDLQARVLAS
SSDQAAEFTD MEGESSAVTS PFPALTSTTP NELEMTNKNS NVVGGMTHSN SMPTLTAAKD
GNTKVLPFEF RALEVCLESA CRSLEEETST LEQEAYPALD ELTSKISTLN LERVRQIKSR
LVAISGRVQK VRDELEHLLD DEMDMAEMYL TEKLTRQEIS ETSSRVEVDD PSQLEVDRDE
DYRSEADVSN GTFIGYKPHI EELEMLLEAY FVQIDGTLNK LSHLREYVDD TEDYINIMLD
DKQNQLLQMG VMLSTATVVI TAGVAVVGLF GMNIGISLYA DPTNEEEKRA SNMKFWETTL
GTIAGCTVMY IVAMGWGKRS GLLQ
