MRS2I_ARATH
ID MRS2I_ARATH Reviewed; 294 AA.
AC P0CZ22; Q682I2; Q8H1G7; Q9FXX0; Q9LXD5;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 1.
DT 03-AUG-2022, entry version 51.
DE RecName: Full=Putative inactive magnesium transporter MRS2-8;
DE AltName: Full=Magnesium Transporter 8;
DE Short=AtMGT8;
GN Name=MRS2-8; Synonyms=MGT8; OrderedLocusNames=At5g09720;
GN ORFNames=F17I14.90, MTH16.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10470850; DOI=10.1093/dnares/6.3.183;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Kotani H.,
RA Miyajima N., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. IX. Sequence
RT features of the regions of 1,011,550 bp covered by seventeen P1 and TAC
RT clones.";
RL DNA Res. 6:183-195(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=19966073; DOI=10.1105/tpc.109.070557;
RA Gebert M., Meschenmoser K., Svidova S., Weghuber J., Schweyen R.,
RA Eifler K., Lenz H., Weyand K., Knoop V.;
RT "A root-expressed magnesium transporter of the MRS2/MGT gene family in
RT Arabidopsis thaliana allows for growth in low-Mg2+ environments.";
RL Plant Cell 21:4018-4030(2009).
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC 1.A.35.5) family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. In strain cv. Columbia,
CC a naturally occurring frameshift at position 277 results in a truncated
CC MRS2-8 protein lacking the two transmembrane regions, which are
CC conserved features of the family. A complete sequence for MRS2-8 can be
CC found in strain cv. Landsberg erecta (AC P0CZ21). {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB09530.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB89358.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB020752; BAB09530.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL353994; CAB89358.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED91438.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM69671.1; -; Genomic_DNA.
DR EMBL; AK175385; BAD43148.1; -; mRNA.
DR RefSeq; NP_001331333.1; NM_001343066.1.
DR RefSeq; NP_196534.4; NM_121009.5.
DR AlphaFoldDB; P0CZ22; -.
DR SMR; P0CZ22; -.
DR STRING; 3702.AT5G09720.1; -.
DR PaxDb; P0CZ22; -.
DR PRIDE; P0CZ22; -.
DR EnsemblPlants; AT5G09720.1; AT5G09720.1; AT5G09720.
DR EnsemblPlants; AT5G09720.2; AT5G09720.2; AT5G09720.
DR GeneID; 830831; -.
DR Gramene; AT5G09720.1; AT5G09720.1; AT5G09720.
DR Gramene; AT5G09720.2; AT5G09720.2; AT5G09720.
DR KEGG; ath:AT5G09720; -.
DR Araport; AT5G09720; -.
DR TAIR; locus:2144746; AT5G09720.
DR eggNOG; KOG2662; Eukaryota.
DR HOGENOM; CLU_034694_1_0_1; -.
DR InParanoid; P0CZ22; -.
DR OMA; FHIHARD; -.
DR OrthoDB; 1363588at2759; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; P0CZ22; baseline and differential.
DR Genevisible; P0CZ22; AT.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015693; P:magnesium ion transport; IBA:GO_Central.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890; PTHR13890; 1.
PE 5: Uncertain;
KW Coiled coil; Reference proteome.
FT CHAIN 1..294
FT /note="Putative inactive magnesium transporter MRS2-8"
FT /id="PRO_0000411107"
FT COILED 179..216
FT /evidence="ECO:0000255"
SQ SEQUENCE 294 AA; 33096 MW; F504AB7A042585B0 CRC64;
MLPNEELVPV KRITPQSSWS WISIDATGKK TVLDVDKYVI MHRVQIHARD LRILDPNLFY
PSAILGRERA IVLNLEHIKA IITAKEVLIQ DSSDENLIPT LEEFQTRLSV GNKAHGGQLD
GDVVEEDESA FEFRALEVAL EAICSFLAAR TIELEKSAYP ALDELTLKLT SRNLLRVCKL
KSSMTRLTAQ VQKIKDELEQ LLEDDEDMAE LYLSRKLAGA SSPAIDSGEH INWYPTSPTI
GAKISRAKSH LVRSATVRGD DKNDVEEVEM LLEAHFYANR QNFEQINRAT RVCG
