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MRS2I_ORYSI
ID   MRS2I_ORYSI             Reviewed;         381 AA.
AC   B8AJT9;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Magnesium transporter MRS2-I;
GN   Name=MRS2-I; ORFNames=OsI_13458;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA   Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA   Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA   Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA   Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA   Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA   Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA   Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA   Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA   Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA   Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA   Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA   McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
CC   -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC       magnesium. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC       1.A.35.5) family. {ECO:0000305}.
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DR   EMBL; CM000128; EEC76157.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8AJT9; -.
DR   SMR; B8AJT9; -.
DR   STRING; 39946.B8AJT9; -.
DR   EnsemblPlants; BGIOSGA009838-TA; BGIOSGA009838-PA; BGIOSGA009838.
DR   Gramene; BGIOSGA009838-TA; BGIOSGA009838-PA; BGIOSGA009838.
DR   HOGENOM; CLU_034694_1_0_1; -.
DR   OMA; TQHDVEG; -.
DR   Proteomes; UP000007015; Chromosome 3.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   InterPro; IPR039204; MRS2-like.
DR   PANTHER; PTHR13890; PTHR13890; 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF144083; SSF144083; 1.
PE   3: Inferred from homology;
KW   Ion transport; Magnesium; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..381
FT                   /note="Magnesium transporter MRS2-I"
FT                   /id="PRO_0000394282"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   MOTIF           336..338
FT                   /note="Required for magnesium transport activity"
SQ   SEQUENCE   381 AA;  41976 MW;  EF4E24B1C4C35A49 CRC64;
     MAAAVVVAGE AAAAAGAGGK KRGASRSWIL FDAAGEERVL DADKYAIMHR VDINARDLRI
     LDPLLSYPST ILGRERAIVL NLEHIKAIIT AEEVLLRDPL DDNVIPVVEE LRRRLAPSSA
     TQHDVEGAEE DESPFEFRAL EVTLEAICSF LGARTTELES AAYPALDELT SKISSRNLDR
     VRKLKSGMTR LNARVQKVRD ELEQLLDDDD DMADLYLSRK LAGAASPVSG SGGPNWFPAS
     PTIGSKISRA SRASAPTIHG NENDVEELEM LLEAYFMQID GTLNKLTTLR EYIDDTEDYI
     NIQLDNHRNQ LIQLELFLSS GTVCLSLYSL VAGIFGMNIP YTWNDNHGYV FKWVVLVSGL
     FCAFMFVSIV AYARHKGLVG S
 
 
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