ID   MRT4_ASHGO              Reviewed;         236 AA.
AC   Q75DK9;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Ribosome assembly factor mrt4 {ECO:0000250|UniProtKB:P33201};
DE   AltName: Full=mRNA turnover protein 4 {ECO:0000250|UniProtKB:P33201};
GN   Name=MRT4 {ECO:0000250|UniProtKB:P33201}; OrderedLocusNames=ABR012C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Component of the ribosome assembly machinery. Nuclear paralog
CC       of the ribosomal protein P0, it binds pre-60S subunits at an early
CC       stage of assembly in the nucleolus, and is replaced by P0 in
CC       cytoplasmic pre-60S subunits and mature 80S ribosomes.
CC       {ECO:0000250|UniProtKB:P33201}.
CC   -!- SUBUNIT: Associates with the pre-60S ribosomal particle.
CC       {ECO:0000250|UniProtKB:P33201}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:P33201}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P33201}. Note=Shuttles between the nucleus and
CC       the cytoplasm. {ECO:0000250|UniProtKB:P33201}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC       {ECO:0000305}.
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DR   EMBL; AE016815; AAS50782.1; -; Genomic_DNA.
DR   RefSeq; NP_982958.1; NM_208311.1.
DR   AlphaFoldDB; Q75DK9; -.
DR   SMR; Q75DK9; -.
DR   STRING; 33169.AAS50782; -.
DR   EnsemblFungi; AAS50782; AAS50782; AGOS_ABR012C.
DR   GeneID; 4619050; -.
DR   KEGG; ago:AGOS_ABR012C; -.
DR   eggNOG; KOG0816; Eukaryota.
DR   HOGENOM; CLU_071690_0_0_1; -.
DR   InParanoid; Q75DK9; -.
DR   OMA; LEWAENY; -.
DR   Proteomes; UP000000591; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0005654; C:nucleoplasm; IEA:EnsemblFungi.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IEA:InterPro.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:EnsemblFungi.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   CDD; cd05796; Ribosomal_P0_like; 1.
DR   Gene3D; 3.30.70.1730; -; 1.
DR   Gene3D; 3.90.105.20; -; 1.
DR   InterPro; IPR033867; Mrt4.
DR   InterPro; IPR043141; Ribosomal_L10-like_sf.
DR   InterPro; IPR001790; Ribosomal_L10P.
DR   InterPro; IPR043164; RL10_insert_sf.
DR   InterPro; IPR040637; RL10P_insert.
DR   Pfam; PF00466; Ribosomal_L10; 1.
DR   Pfam; PF17777; RL10P_insert; 1.
DR   SUPFAM; SSF160369; SSF160369; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..236
FT                   /note="Ribosome assembly factor mrt4"
FT                   /id="PRO_0000154811"
SQ   SEQUENCE   236 AA;  26879 MW;  E5D4825D51E60032 CRC64;
     MPRSKRSKLV TLAQTEKKGR ENKERIFDEV RQALDTYRYV WVLRLEDVRT PVLQEIRSAW
     AGSKLIMGRR KVLEKALGGT RETEYKENVS GLVKQCEGMC GLLFTDETPE TVTAYFREYR
     KADYSRAKSR APLRVEIPAG VVYSRGGQVP AEDDVPMVHS LEPTLRNKFK MPTRIQNGKI
     TLEQPYLVCE AGETLDVRQA LILKQFGVAA AEFRVKLAAY YDGEAAAVEE VRINME