ID   MRT4_BOVIN              Reviewed;         239 AA.
AC   A4FV84;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=mRNA turnover protein 4 homolog {ECO:0000250|UniProtKB:P33201};
DE   AltName: Full=Ribosome assembly factor MRTO4 {ECO:0000250|UniProtKB:P33201, ECO:0000305};
GN   Name=MRTO4;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Hippocampus;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the ribosome assembly machinery. Nuclear paralog
CC       of the ribosomal protein P0, it binds pre-60S subunits at an early
CC       stage of assembly in the nucleolus, and is replaced by P0 in
CC       cytoplasmic pre-60S subunits and mature 80S ribosomes.
CC       {ECO:0000250|UniProtKB:P33201}.
CC   -!- SUBUNIT: Associates with the pre-60S ribosomal particle. Interacts with
CC       MINAS-60 (product of an alternative open reading frame of RBM10).
CC       {ECO:0000250|UniProtKB:Q9UKD2}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:P33201}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P33201}. Note=Shuttles between the nucleus and
CC       the cytoplasm. {ECO:0000250|UniProtKB:P33201}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC       {ECO:0000305}.
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DR   EMBL; BC123852; AAI23853.1; -; mRNA.
DR   RefSeq; NP_001076868.1; NM_001083399.1.
DR   AlphaFoldDB; A4FV84; -.
DR   SMR; A4FV84; -.
DR   STRING; 9913.ENSBTAP00000015861; -.
DR   PaxDb; A4FV84; -.
DR   PRIDE; A4FV84; -.
DR   Ensembl; ENSBTAT00000015861; ENSBTAP00000015861; ENSBTAG00000011951.
DR   GeneID; 509932; -.
DR   KEGG; bta:509932; -.
DR   CTD; 51154; -.
DR   VEuPathDB; HostDB:ENSBTAG00000011951; -.
DR   VGNC; VGNC:31680; MRTO4.
DR   eggNOG; KOG0816; Eukaryota.
DR   GeneTree; ENSGT00390000006238; -.
DR   HOGENOM; CLU_071690_3_0_1; -.
DR   InParanoid; A4FV84; -.
DR   OMA; LEWAENY; -.
DR   OrthoDB; 1181992at2759; -.
DR   TreeFam; TF300111; -.
DR   Proteomes; UP000009136; Chromosome 2.
DR   Bgee; ENSBTAG00000011951; Expressed in saliva-secreting gland and 107 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IBA:GO_Central.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IEA:InterPro.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0006364; P:rRNA processing; IBA:GO_Central.
DR   CDD; cd05796; Ribosomal_P0_like; 1.
DR   Gene3D; 3.30.70.1730; -; 1.
DR   Gene3D; 3.90.105.20; -; 1.
DR   InterPro; IPR033867; Mrt4.
DR   InterPro; IPR043141; Ribosomal_L10-like_sf.
DR   InterPro; IPR001790; Ribosomal_L10P.
DR   InterPro; IPR043164; RL10_insert_sf.
DR   InterPro; IPR040637; RL10P_insert.
DR   Pfam; PF00466; Ribosomal_L10; 1.
DR   Pfam; PF17777; RL10P_insert; 1.
DR   SUPFAM; SSF160369; SSF160369; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Phosphoprotein; Reference proteome;
KW   Ribosome biogenesis.
FT   CHAIN           1..239
FT                   /note="mRNA turnover protein 4 homolog"
FT                   /id="PRO_0000319317"
FT   REGION          216..239
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..239
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         225
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9D0I8"
FT   MOD_RES         229
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9D0I8"
FT   MOD_RES         233
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9D0I8"
SQ   SEQUENCE   239 AA;  27526 MW;  C7BEA8C4109FF068 CRC64;
     MPKSKRDKKV SLTKTAKKGL ELKQNLIEEL RKCVDTYKYL FIFSVANMRN SKLKDIRNAW
     KHSRMFFGKN KVMMVALGRS PSDEYKDNLH QVSKKLRGEV GLLFTNRTKE EVDEWFTKYT
     EMDYARAGNK ATFTVNLDPG PLEQFPHSME PQLRQLGLPT ALKKGVVTLL SDYEVCKEGD
     VLTPEQARVL KLFGYEMAEF KVSIKYMWDA QSGRFQQMGD DLPESAPESE GESEEEDDS