ID   MRT4_CANGA              Reviewed;         239 AA.
AC   Q6FJ04;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Ribosome assembly factor mrt4 {ECO:0000250|UniProtKB:P33201};
DE   AltName: Full=mRNA turnover protein 4 {ECO:0000250|UniProtKB:P33201};
GN   Name=MRT4 {ECO:0000250|UniProtKB:P33201}; OrderedLocusNames=CAGL0M10197g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the ribosome assembly machinery. Nuclear paralog
CC       of the ribosomal protein P0, it binds pre-60S subunits at an early
CC       stage of assembly in the nucleolus, and is replaced by P0 in
CC       cytoplasmic pre-60S subunits and mature 80S ribosomes.
CC       {ECO:0000250|UniProtKB:P33201}.
CC   -!- SUBUNIT: Associates with the pre-60S ribosomal particle.
CC       {ECO:0000250|UniProtKB:P33201}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:P33201}. Cytoplasm
CC       {ECO:0000250|UniProtKB:P33201}. Note=Shuttles between the nucleus and
CC       the cytoplasm. {ECO:0000250|UniProtKB:P33201}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uL10 family.
CC       {ECO:0000305}.
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DR   EMBL; CR380959; CAG62768.1; -; Genomic_DNA.
DR   RefSeq; XP_449790.1; XM_449790.1.
DR   AlphaFoldDB; Q6FJ04; -.
DR   SMR; Q6FJ04; -.
DR   STRING; 5478.XP_449790.1; -.
DR   EnsemblFungi; CAG62768; CAG62768; CAGL0M10197g.
DR   GeneID; 2891354; -.
DR   KEGG; cgr:CAGL0M10197g; -.
DR   CGD; CAL0137229; CAGL0M10197g.
DR   VEuPathDB; FungiDB:CAGL0M10197g; -.
DR   eggNOG; KOG0816; Eukaryota.
DR   HOGENOM; CLU_071690_0_0_1; -.
DR   InParanoid; Q6FJ04; -.
DR   OMA; LEWAENY; -.
DR   Proteomes; UP000002428; Chromosome M.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:EnsemblFungi.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IEA:EnsemblFungi.
DR   GO; GO:0032040; C:small-subunit processome; IEA:EnsemblFungi.
DR   GO; GO:0000956; P:nuclear-transcribed mRNA catabolic process; IEA:EnsemblFungi.
DR   GO; GO:0000027; P:ribosomal large subunit assembly; IEA:InterPro.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:EnsemblFungi.
DR   GO; GO:0006364; P:rRNA processing; IEA:EnsemblFungi.
DR   CDD; cd05796; Ribosomal_P0_like; 1.
DR   Gene3D; 3.30.70.1730; -; 1.
DR   Gene3D; 3.90.105.20; -; 1.
DR   InterPro; IPR033867; Mrt4.
DR   InterPro; IPR043141; Ribosomal_L10-like_sf.
DR   InterPro; IPR001790; Ribosomal_L10P.
DR   InterPro; IPR043164; RL10_insert_sf.
DR   InterPro; IPR040637; RL10P_insert.
DR   Pfam; PF00466; Ribosomal_L10; 1.
DR   Pfam; PF17777; RL10P_insert; 1.
DR   SUPFAM; SSF160369; SSF160369; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..239
FT                   /note="Ribosome assembly factor mrt4"
FT                   /id="PRO_0000154812"
SQ   SEQUENCE   239 AA;  27381 MW;  CB701D241F09B6E0 CRC64;
     MPRSKRSKLV TLAQTDKKGR ENKERIFDEV REALDTYKYV FVLQLDDVRT PVLQEIREAW
     VGSKLLMGKR KVLEKALGTT REQEYKENLS KLTKYCSGVI GLLFTNETLD TVKEYFEAYS
     RLDYSRPNSR APITFEVPEG IVYSRGGQIP IEEDVPMAHS LEPTLRNKYE MPTKIKAGKI
     TLEAPYLVCK EGQKLDVRQA LILKQFGVAL AQFKVIISAY YDNESSTVSE LNINKKQDA