MS2B_DROME
ID MS2B_DROME Reviewed; 90 AA.
AC P10334; A0JQ48; A4V091; O76300; O76302; O77456; O97184; O97185; O97456;
AC O97460; Q4V3V8; Q95NY1; Q95NY2; Q95NY3; Q9V432;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=Accessory gland-specific peptide 26Ab;
DE AltName: Full=Male accessory gland secretory protein 355B;
DE Flags: Precursor;
GN Name=Acp26Ab {ECO:0000312|FlyBase:FBgn0002856};
GN Synonyms=msp355b {ECO:0000303|PubMed:3142802}, Mst26Ab,
GN mst355b {ECO:0000303|PubMed:3142802};
GN ORFNames=CG9024 {ECO:0000312|FlyBase:FBgn0002856};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Canton-S;
RX PubMed=3142802; DOI=10.1101/gad.2.9.1063;
RA Monsma S.A., Wolfner M.F.;
RT "Structure and expression of a Drosophila male accessory gland gene whose
RT product resembles a peptide pheromone precursor.";
RL Genes Dev. 2:1063-1073(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=NC-001, NC-002, NC-003, NC-004, NC-005, NC-006, NC-007, NC-008,
RC NC-009, and NC-010;
RX PubMed=1361475; DOI=10.1093/genetics/132.3.755;
RA Aguade M., Miyashita N., Langley C.H.;
RT "Polymorphism and divergence in the Mst26A male accessory gland gene region
RT in Drosophila.";
RL Genetics 132:755-770(1992).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS HIS-64; VAL-80; ILE-89 AND
RP GLU-90.
RC STRAIN=La10, La105, La106, La108, La116, La118, La120, La125, La13, La14,
RC La15, La25, La27, La28, La3, La31, La32, La36, La37, La46, La54, La58,
RC La60, La62, Ma11, Ma18, Ma20, Ma21, Ma23, Ma24, Ma3, Ma31, Ma35, Ma37,
RC Ma43, Ma50, Ma53, Ma56, Ma57, Ma6, Ma60, Ma74, Mo13a, Mo29b, Mo34a, Mo36a,
RC Mo37a, Mo40b, Mo47a, Mo52b, Mo79b, and Mo80b;
RX PubMed=9799260; DOI=10.1093/genetics/150.3.1079;
RA Aguade M.;
RT "Different forces drive the evolution of the Acp26Aa and Acp26Ab accessory
RT gland genes in the Drosophila melanogaster species complex.";
RL Genetics 150:1079-1089(1998).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS HIS-64; ARG-77; VAL-80;
RP ILE-89 AND GLU-90.
RC STRAIN=AF1, AF10, AF2, AF3, AF4, AF5, AF6, AF7, AF8, AF9, Au1, Au10, Au2,
RC Au3, Au4, Au5, Au6, Au7, Au8, Au9, NC-001, NC-002, NC-003, NC-004, NC-005,
RC NC-006, NC-007, NC-008, NC-010, NC-098, Ny1, Ny2, Ny3, Ny4, Ny5, Ny6, Ny7,
RC Ny8, TW1, TW10, TW11, TW2, TW3, TW4, TW5, TW6, TW7, TW8, and TW9;
RX PubMed=9718731; DOI=10.1093/oxfordjournals.molbev.a026002;
RA Tsaur S.-C., Ting C.-T., Wu C.-I.;
RT "Positive selection driving the evolution of a gene of male reproduction,
RT Acp26Aa, of Drosophila: II. Divergence versus polymorphism.";
RL Mol. Biol. Evol. 15:1040-1046(1998).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley;
RA Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A., Kapadia B.,
RA Pacleb J.M., Park S., Wan K.H., Yu C., Celniker S.E.;
RL Submitted (NOV-2006) to the EMBL/GenBank/DDBJ databases.
RN [8]
RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=2257979; DOI=10.1016/0012-1606(90)90368-s;
RA Monsma S.A., Harada H.A., Wolfner M.F.;
RT "Synthesis of two Drosophila male accessory gland proteins and their fate
RT after transfer to the female during mating.";
RL Dev. Biol. 142:465-475(1990).
CC -!- FUNCTION: This protein is transferred from male to female during mating
CC and may affect egglaying and behavior after mating.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space. Cytoplasm
CC {ECO:0000269|PubMed:2257979}.
CC -!- TISSUE SPECIFICITY: Main cells and secondary cells of the accessory
CC glands of 1 day old virgin males (at protein level) (PubMed:2257979).
CC In 5 day old virgin males, only detected in the secondary cells (at
CC protein level) (PubMed:2257979). Reappears in the main cells after
CC mating (at protein level) (PubMed:2257979). First detected in adult
CC males 3-4 hr after eclosion, levels increase reaching a peak at day 3-5
CC which is maintained until at least day 10 of adulthood (at protein
CC level) (PubMed:2257979). In unmated male adults, levels are maintained
CC for the first 6 days of adulthood and then gradually decrease for at
CC least the next 8 days (PubMed:2257979). No expression in females
CC (PubMed:3142802). {ECO:0000269|PubMed:2257979,
CC ECO:0000269|PubMed:3142802}.
CC -!- INDUCTION: Up-regulated in response to mating.
CC {ECO:0000269|PubMed:2257979}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK57075.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; Y00219; CAA68367.1; -; Genomic_DNA.
DR EMBL; X70888; CAA50233.1; -; Genomic_DNA.
DR EMBL; X70889; CAA50235.1; -; Genomic_DNA.
DR EMBL; X70890; CAA50237.1; -; Genomic_DNA.
DR EMBL; X70891; CAA50239.1; -; Genomic_DNA.
DR EMBL; X70892; CAA50241.1; -; Genomic_DNA.
DR EMBL; X70893; CAA50243.1; -; Genomic_DNA.
DR EMBL; X70894; CAA50245.1; -; Genomic_DNA.
DR EMBL; X70895; CAA50247.1; -; Genomic_DNA.
DR EMBL; X70896; CAA50249.1; -; Genomic_DNA.
DR EMBL; X70897; CAA50251.1; -; Genomic_DNA.
DR EMBL; AJ231350; CAB37195.1; -; Genomic_DNA.
DR EMBL; AJ231351; CAB37197.1; -; Genomic_DNA.
DR EMBL; AJ231352; CAB37199.1; -; Genomic_DNA.
DR EMBL; AJ231353; CAB37201.1; -; Genomic_DNA.
DR EMBL; AJ231354; CAB37203.1; -; Genomic_DNA.
DR EMBL; AJ231355; CAB37205.1; -; Genomic_DNA.
DR EMBL; AJ231356; CAB37207.1; -; Genomic_DNA.
DR EMBL; AJ231357; CAB37209.1; -; Genomic_DNA.
DR EMBL; AJ231358; CAB37211.1; -; Genomic_DNA.
DR EMBL; AJ231359; CAB37213.1; -; Genomic_DNA.
DR EMBL; AJ231360; CAB37215.1; -; Genomic_DNA.
DR EMBL; AJ231361; CAB37217.1; -; Genomic_DNA.
DR EMBL; AJ231362; CAB37219.1; -; Genomic_DNA.
DR EMBL; AJ231363; CAB37221.1; -; Genomic_DNA.
DR EMBL; AJ231364; CAB37223.1; -; Genomic_DNA.
DR EMBL; AJ231365; CAB37225.1; -; Genomic_DNA.
DR EMBL; AJ231366; CAB37227.1; -; Genomic_DNA.
DR EMBL; AJ231367; CAB37229.1; -; Genomic_DNA.
DR EMBL; AJ231368; CAB37231.1; -; Genomic_DNA.
DR EMBL; AJ231369; CAB37233.1; -; Genomic_DNA.
DR EMBL; AJ231370; CAB37235.1; -; Genomic_DNA.
DR EMBL; AJ231371; CAB37237.1; -; Genomic_DNA.
DR EMBL; AJ231372; CAB37239.1; -; Genomic_DNA.
DR EMBL; AJ231373; CAB37241.1; -; Genomic_DNA.
DR EMBL; AJ231374; CAB37624.1; -; Genomic_DNA.
DR EMBL; AJ231375; CAB37243.1; -; Genomic_DNA.
DR EMBL; AJ231376; CAB37245.1; -; Genomic_DNA.
DR EMBL; AJ231377; CAB37247.1; -; Genomic_DNA.
DR EMBL; AJ231378; CAB37249.1; -; Genomic_DNA.
DR EMBL; AJ231379; CAB37251.1; -; Genomic_DNA.
DR EMBL; AJ231380; CAB37253.1; -; Genomic_DNA.
DR EMBL; AJ231381; CAB37255.1; -; Genomic_DNA.
DR EMBL; AJ231382; CAB37257.1; -; Genomic_DNA.
DR EMBL; AJ231383; CAB37259.1; -; Genomic_DNA.
DR EMBL; AJ231384; CAB37261.1; -; Genomic_DNA.
DR EMBL; AJ231385; CAB37263.1; -; Genomic_DNA.
DR EMBL; AJ231386; CAB37265.1; -; Genomic_DNA.
DR EMBL; AJ231387; CAB37267.1; -; Genomic_DNA.
DR EMBL; AJ231388; CAB37269.1; -; Genomic_DNA.
DR EMBL; AJ231389; CAB37271.1; -; Genomic_DNA.
DR EMBL; AJ231390; CAB37273.1; -; Genomic_DNA.
DR EMBL; AJ231391; CAB37275.1; -; Genomic_DNA.
DR EMBL; AJ231392; CAB37277.1; -; Genomic_DNA.
DR EMBL; AJ231393; CAB37279.1; -; Genomic_DNA.
DR EMBL; AJ231394; CAB37281.1; -; Genomic_DNA.
DR EMBL; AJ231395; CAB37283.1; -; Genomic_DNA.
DR EMBL; AJ231396; CAB37285.1; -; Genomic_DNA.
DR EMBL; AJ231397; CAB37287.1; -; Genomic_DNA.
DR EMBL; AJ231398; CAB37289.1; -; Genomic_DNA.
DR EMBL; AJ231399; CAB37291.1; -; Genomic_DNA.
DR EMBL; AJ231400; CAB37293.1; -; Genomic_DNA.
DR EMBL; AJ231401; CAB37629.1; -; Genomic_DNA.
DR EMBL; AF052470; AAC27996.1; -; Genomic_DNA.
DR EMBL; AF052471; AAC27998.1; -; Genomic_DNA.
DR EMBL; AF052472; AAC28000.1; -; Genomic_DNA.
DR EMBL; AF052473; AAC28002.1; -; Genomic_DNA.
DR EMBL; AF052474; AAC28004.1; -; Genomic_DNA.
DR EMBL; AF052475; AAC28006.1; -; Genomic_DNA.
DR EMBL; AF052476; AAC28008.1; -; Genomic_DNA.
DR EMBL; AF052477; AAC28010.1; -; Genomic_DNA.
DR EMBL; AF052478; AAC28012.1; -; Genomic_DNA.
DR EMBL; AF052479; AAC28014.1; -; Genomic_DNA.
DR EMBL; AF052480; AAC28016.1; -; Genomic_DNA.
DR EMBL; AF052481; AAC28018.1; -; Genomic_DNA.
DR EMBL; AF053250; AAC28791.1; -; Genomic_DNA.
DR EMBL; AF053251; AAC28793.1; -; Genomic_DNA.
DR EMBL; AF053252; AAC28795.1; -; Genomic_DNA.
DR EMBL; AF053253; AAC28797.1; -; Genomic_DNA.
DR EMBL; AF053254; AAC28799.1; -; Genomic_DNA.
DR EMBL; AF053255; AAC28801.1; -; Genomic_DNA.
DR EMBL; AF053256; AAC28803.1; -; Genomic_DNA.
DR EMBL; AF053257; AAC28805.1; -; Genomic_DNA.
DR EMBL; AF053258; AAC28807.1; -; Genomic_DNA.
DR EMBL; AF053259; AAC28809.1; -; Genomic_DNA.
DR EMBL; AF053260; AAC28811.1; -; Genomic_DNA.
DR EMBL; AF053261; AAC28813.1; -; Genomic_DNA.
DR EMBL; AF053262; AAC28815.1; -; Genomic_DNA.
DR EMBL; AF053263; AAC28817.1; -; Genomic_DNA.
DR EMBL; AF053264; AAC28819.1; -; Genomic_DNA.
DR EMBL; AF053265; AAC28821.1; -; Genomic_DNA.
DR EMBL; AF053266; AAC28823.1; -; Genomic_DNA.
DR EMBL; AF053267; AAC28825.1; -; Genomic_DNA.
DR EMBL; AF053268; AAC28827.1; -; Genomic_DNA.
DR EMBL; AF053269; AAC28829.1; -; Genomic_DNA.
DR EMBL; AF053270; AAC28831.1; -; Genomic_DNA.
DR EMBL; AF053271; AAC28833.1; -; Genomic_DNA.
DR EMBL; AF053272; AAC28835.1; -; Genomic_DNA.
DR EMBL; AF053273; AAC28837.1; -; Genomic_DNA.
DR EMBL; AF053274; AAC28839.1; -; Genomic_DNA.
DR EMBL; AF053275; AAC28841.1; -; Genomic_DNA.
DR EMBL; AF053276; AAC28843.1; -; Genomic_DNA.
DR EMBL; AE014134; AAF52297.1; -; Genomic_DNA.
DR EMBL; AE014134; AAN10560.1; -; Genomic_DNA.
DR EMBL; BT023248; AAY55664.1; -; mRNA.
DR EMBL; BT029418; ABK57075.1; ALT_INIT; mRNA.
DR PIR; S02854; S02854.
DR PIR; S30412; S30412.
DR RefSeq; NP_001285646.1; NM_001298717.1.
DR RefSeq; NP_476645.1; NM_057297.3.
DR RefSeq; NP_599099.1; NM_134272.1.
DR AlphaFoldDB; P10334; -.
DR STRING; 7227.FBpp0078788; -.
DR PaxDb; P10334; -.
DR DNASU; 33816; -.
DR EnsemblMetazoa; FBtr0079156; FBpp0078787; FBgn0002856.
DR EnsemblMetazoa; FBtr0079157; FBpp0078788; FBgn0002856.
DR EnsemblMetazoa; FBtr0342618; FBpp0309554; FBgn0002856.
DR GeneID; 33816; -.
DR KEGG; dme:Dmel_CG9024; -.
DR CTD; 33816; -.
DR FlyBase; FBgn0002856; Acp26Ab.
DR VEuPathDB; VectorBase:FBgn0002856; -.
DR HOGENOM; CLU_187897_0_0_1; -.
DR InParanoid; P10334; -.
DR OMA; SCICLWQ; -.
DR OrthoDB; 1613893at2759; -.
DR PhylomeDB; P10334; -.
DR BioGRID-ORCS; 33816; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 33816; -.
DR PRO; PR:P10334; -.
DR Proteomes; UP000000803; Chromosome 2L.
DR Bgee; FBgn0002856; Expressed in male reproductive gland and 7 other tissues.
DR ExpressionAtlas; P10334; differential.
DR Genevisible; P10334; DM.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005576; C:extracellular region; ISM:FlyBase.
DR GO; GO:0005615; C:extracellular space; HDA:FlyBase.
DR GO; GO:0007617; P:mating behavior; IEA:InterPro.
DR GO; GO:0019953; P:sexual reproduction; IEP:FlyBase.
DR InterPro; IPR008392; Acp26Ab.
DR Pfam; PF05777; Acp26Ab; 1.
PE 1: Evidence at protein level;
KW Behavior; Cytoplasm; Reference proteome; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..90
FT /note="Accessory gland-specific peptide 26Ab"
FT /id="PRO_0000021759"
FT VARIANT 64
FT /note="Q -> H (in strain: AF1, AF2, AF3, AF5, AF6, AF7,
FT AF8, AF9, AF10, Au4, Au7, Au8, La3, La10, La13, La14, La15,
FT La28, La31, La32, La36, La37, La54, La58, La60, La62,
FT La105, La106, La116, La118, La120, La125, Ma3, Ma6, Ma11,
FT Ma18, Ma20, Ma21, Ma23, Ma24, Ma31, Ma35, Ma37, Ma43, Ma50,
FT Ma53, Ma56, Ma57, Ma60, Ma74, Mo29b, Mo40b, Mo52b, NC-003,
FT NC-004, NC-006, NC-008, NC-009, Ny2, Ny3, Ny4, Ny5, TW1,
FT TW2, TW5, TW6, TW7, TW8, TW10 and TW11)"
FT /evidence="ECO:0000269|PubMed:9718731,
FT ECO:0000269|PubMed:9799260"
FT VARIANT 77
FT /note="P -> R (in strain: TW9)"
FT /evidence="ECO:0000269|PubMed:9718731"
FT VARIANT 80
FT /note="I -> V (in strain: La3, La10, La13, La15, La27,
FT La28, La31, La62, La105, La106, La116, La118, La120, Ma3,
FT Ma6, Ma18, Ma23, Ma31, Ma37, Ma43, Ma56, Ma57, Ma60, Ma74,
FT Mo13a, Mo29b, Mo34a, Mo40b, Mo52b, NC-002, NC-003, NC-004,
FT NC-006, NC-008, Ny2, Ny4, TW2, TW4, TW5, TW8, TW10 and
FT TW11)"
FT /evidence="ECO:0000269|PubMed:9718731,
FT ECO:0000269|PubMed:9799260"
FT VARIANT 89
FT /note="M -> I (in strain: Au4 and Ma60)"
FT /evidence="ECO:0000269|PubMed:9718731,
FT ECO:0000269|PubMed:9799260"
FT VARIANT 90
FT /note="A -> E (in strain: AF1, AF2, AF3, AF5, AF6, AF7,
FT AF8, AF9, AF10, La14, La31, La32, La60, La106, La118,
FT La125, Ma6, Ma21, Ma24, Ma31, Ma37, Ma50, Ma56, Ma57, Ma74,
FT TW1 and TW6)"
FT /evidence="ECO:0000269|PubMed:9718731,
FT ECO:0000269|PubMed:9799260"
SQ SEQUENCE 90 AA; 10162 MW; 1FDFDC7951F9BDFF CRC64;
MNYFAVICIF SCICLWQFSD AAPFISVQSS SQSRSQKVMN GMLRTLYDYS VQDSVNDATG
HLIQTHKADF NSDVMSPDEI ESVRQQLNMA
