MS57A_DROME
ID MS57A_DROME Reviewed; 75 AA.
AC Q9VBL6; Q24390; Q8MSH9;
DT 19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=Accessory gland-specific peptide 57Da;
DE AltName: Full=Male accessory gland secretory protein 57Da;
DE Flags: Precursor;
GN Name=Mst57Da; ORFNames=CG9074;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
RC STRAIN=Oregon-R;
RX PubMed=7711745; DOI=10.1016/0965-1748(94)00034-f;
RA Simmerl E., Schaefer M., Schaefer U.;
RT "Structure and regulation of a gene cluster for male accessory gland
RT transcripts in Drosophila melanogaster.";
RL Insect Biochem. Mol. Biol. 25:127-137(1995).
RN [2] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-75.
RC STRAIN=Berkeley; TISSUE=Head;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- FUNCTION: Transferred from male to female during mating and may affect
CC egglaying and behavior after mating.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:7711745}.
CC -!- TISSUE SPECIFICITY: Lumen fluid of male accessory glands, becomes
CC seminal fluid. {ECO:0000269|PubMed:7711745}.
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DR EMBL; Z33647; CAA83925.1; -; Genomic_DNA.
DR EMBL; AE014297; AAF56515.1; -; Genomic_DNA.
DR EMBL; AY118802; AAM50662.1; -; mRNA.
DR RefSeq; NP_524906.1; NM_080167.4.
DR AlphaFoldDB; Q9VBL6; -.
DR BioGRID; 71071; 1.
DR DIP; DIP-20402N; -.
DR IntAct; Q9VBL6; 21.
DR STRING; 7227.FBpp0084288; -.
DR PaxDb; Q9VBL6; -.
DR PRIDE; Q9VBL6; -.
DR DNASU; 47954; -.
DR EnsemblMetazoa; FBtr0084914; FBpp0084288; FBgn0011668.
DR GeneID; 47954; -.
DR KEGG; dme:Dmel_CG9074; -.
DR CTD; 47954; -.
DR FlyBase; FBgn0011668; Mst57Da.
DR VEuPathDB; VectorBase:FBgn0011668; -.
DR HOGENOM; CLU_2833890_0_0_1; -.
DR OMA; ANPRQQY; -.
DR SignaLink; Q9VBL6; -.
DR BioGRID-ORCS; 47954; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 47954; -.
DR PRO; PR:Q9VBL6; -.
DR Proteomes; UP000000803; Chromosome 3R.
DR Bgee; FBgn0011668; Expressed in male reproductive gland and 13 other tissues.
DR ExpressionAtlas; Q9VBL6; baseline and differential.
DR Genevisible; Q9VBL6; DM.
DR GO; GO:0005576; C:extracellular region; ISM:FlyBase.
DR GO; GO:0005615; C:extracellular space; HDA:FlyBase.
DR GO; GO:0018991; P:oviposition; NAS:UniProtKB.
DR GO; GO:0045924; P:regulation of female receptivity; NAS:UniProtKB.
DR GO; GO:0019953; P:sexual reproduction; IEP:FlyBase.
PE 2: Evidence at transcript level;
KW Behavior; Reference proteome; Secreted; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT PEPTIDE 20..75
FT /note="Accessory gland-specific peptide 57Da"
FT /id="PRO_0000021762"
FT REGION 55..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 39..46
FT /note="Missing (in Ref. 1)"
FT /evidence="ECO:0000305"
FT CONFLICT 64..75
FT /note="Missing (in Ref. 1; CAA83925)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 75 AA; 7106 MW; BCD3D70817C98E14 CRC64;
MKFLALFVTL LVVLALVSAQ KSQNTNHNVI VIGAKKPGAA PAAAAAAAPA APPAAAPAAA
PAAPEAGLAD APAES
