MS57B_DROME
ID MS57B_DROME Reviewed; 40 AA.
AC Q9VBL7; Q24391;
DT 19-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Accessory gland-specific peptide 57Db;
DE AltName: Full=Male accessory gland secretory protein 57Db;
DE Flags: Precursor;
GN Name=Mst57Db; ORFNames=CG5016;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], TISSUE SPECIFICITY, AND DEVELOPMENTAL
RP STAGE.
RC STRAIN=Oregon-R; TISSUE=Male accessory gland;
RX PubMed=7711745; DOI=10.1016/0965-1748(94)00034-f;
RA Simmerl E., Schaefer M., Schaefer U.;
RT "Structure and regulation of a gene cluster for male accessory gland
RT transcripts in Drosophila melanogaster.";
RL Insect Biochem. Mol. Biol. 25:127-137(1995).
RN [2] {ECO:0000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
CC -!- FUNCTION: Transferred from male to female during mating and may affect
CC egglaying and behavior after mating.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:7711745}.
CC -!- TISSUE SPECIFICITY: Lumen fluid of male accessory glands, becomes
CC seminal fluid. {ECO:0000269|PubMed:7711745}.
CC -!- DEVELOPMENTAL STAGE: Last day of pupal development and adults.
CC {ECO:0000269|PubMed:7711745}.
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DR EMBL; Z33647; CAA83926.1; -; Genomic_DNA.
DR EMBL; AE014297; AAF56514.1; -; Genomic_DNA.
DR RefSeq; NP_524499.2; NM_079775.5.
DR AlphaFoldDB; Q9VBL7; -.
DR BioGRID; 68028; 3.
DR DIP; DIP-19873N; -.
DR IntAct; Q9VBL7; 1.
DR STRING; 7227.FBpp0084289; -.
DR PaxDb; Q9VBL7; -.
DR EnsemblMetazoa; FBtr0084915; FBpp0084289; FBgn0011669.
DR GeneID; 43122; -.
DR KEGG; dme:Dmel_CG5016; -.
DR CTD; 43122; -.
DR FlyBase; FBgn0011669; Mst57Db.
DR VEuPathDB; VectorBase:FBgn0011669; -.
DR HOGENOM; CLU_3299919_0_0_1; -.
DR BioGRID-ORCS; 43122; 0 hits in 1 CRISPR screen.
DR ChiTaRS; Mst57Db; fly.
DR GenomeRNAi; 43122; -.
DR PRO; PR:Q9VBL7; -.
DR Proteomes; UP000000803; Chromosome 3R.
DR Bgee; FBgn0011669; Expressed in male reproductive gland and 14 other tissues.
DR Genevisible; Q9VBL7; DM.
DR GO; GO:0005576; C:extracellular region; NAS:UniProtKB.
DR GO; GO:0005615; C:extracellular space; HDA:FlyBase.
DR GO; GO:0018991; P:oviposition; NAS:UniProtKB.
DR GO; GO:0045924; P:regulation of female receptivity; NAS:UniProtKB.
DR GO; GO:0019953; P:sexual reproduction; HEP:FlyBase.
PE 2: Evidence at transcript level;
KW Behavior; Reference proteome; Secreted; Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT PEPTIDE 18..40
FT /note="Accessory gland-specific peptide 57Db"
FT /id="PRO_0000021763"
FT CONFLICT 37
FT /note="S -> N (in Ref. 1; CAA83926)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 40 AA; 4184 MW; 66F14C76C2649B50 CRC64;
MKITSALVLL FAGVAFAQSA DPNTNENKNV IHINSPSAAK
