ID   MSA_STAAB               Reviewed;         133 AA.
AC   Q2YY17;
DT   17-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Protein msa;
DE   AltName: Full=Modulator of SarA;
GN   Name=msa; OrderedLocusNames=SAB1257c;
OS   Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bovine RF122 / ET3-1;
RX   PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA   Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT   "Molecular correlates of host specialization in Staphylococcus aureus.";
RL   PLoS ONE 2:E1120-E1120(2007).
CC   -!- FUNCTION: Accessory element involved in the expression of sarA and
CC       several virulence factors. Modulates SarA production and/or function in
CC       a strain-dependent manner. Affects the transcription of the accessory
CC       gene regulator (agr) and genes encoding virulence factors including
CC       alpha toxin (hla) and protein A (spa) (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AJ938182; CAI80946.1; -; Genomic_DNA.
DR   RefSeq; WP_000876212.1; NC_007622.1.
DR   AlphaFoldDB; Q2YY17; -.
DR   SMR; Q2YY17; -.
DR   KEGG; sab:SAB1257c; -.
DR   HOGENOM; CLU_157294_0_0_9; -.
DR   OMA; YNVHLMA; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..133
FT                   /note="Protein msa"
FT                   /id="PRO_0000253057"
FT   TRANSMEM        3..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   133 AA;  15566 MW;  808E749FC05D9CF0 CRC64;
     MKYLILSLVA NLLVFGVLSA IGLNINILAA MMMILVIPIT ISGILFFKTN LDKTYIFFNI
     LFIDFYYYIY NVHLMALPRF NSYIKAEMME LEDIDVLITS KDFGFDEILF FTLYLLLILI
     ILYYLKKQVK TKS