ID   MSC3_ASHGO              Reviewed;         751 AA.
AC   Q74ZL3;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Meiotic sister-chromatid recombination protein 3;
GN   Name=MSC3; OrderedLocusNames=AGR185C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: May be involved in the control of meiotic sister-chromatid
CC       recombination. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC       Note=Cell periphery. {ECO:0000250}.
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DR   EMBL; AE016820; AAS54675.1; -; Genomic_DNA.
DR   RefSeq; NP_986851.1; NM_211913.1.
DR   AlphaFoldDB; Q74ZL3; -.
DR   EnsemblFungi; AAS54675; AAS54675; AGOS_AGR185C.
DR   GeneID; 4623153; -.
DR   KEGG; ago:AGOS_AGR185C; -.
DR   HOGENOM; CLU_372522_0_0_1; -.
DR   InParanoid; Q74ZL3; -.
DR   OMA; EMYMHAL; -.
DR   Proteomes; UP000000591; Chromosome VII.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cell membrane; DNA recombination; Meiosis; Membrane; Reference proteome.
FT   CHAIN           1..751
FT                   /note="Meiotic sister-chromatid recombination protein 3"
FT                   /id="PRO_0000096592"
FT   REGION          54..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          216..290
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          314..410
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          431..504
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          558..610
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        220..257
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..394
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        434..499
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        590..610
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   751 AA;  81930 MW;  B64A5FF5D898CCC1 CRC64;
     MVHLPLSRSR SGRRAVPDLS RYQQFYEADA ADGYSTGSGL SSAAASVASL RRPGVGMGRT
     QSLTGYGRTR SLGAARPSYL GAPPRTYSMS SQRRANSLRS NNGFGPPAVA AGNTITVKTT
     ETKDLQGRTR TVTRQTVKHI NGVRYVETTT TMTMPDGEYP DDFYGFEGDF TAKQTSSGHV
     YQNARGAPDI SDIAEEESLE EYLDARDTAP ALRIQLRAPP RVQQQRQLQR QRRLSDTNFP
     ARRSAKSSPA RQSSEEPPAT TKPHRIRFDE TPQIVGIDPP TQKKAPKKQM TEQEMYMHAL
     DAARKKVYGE ISQPALEAKQ PHRSTMSKRM TLRDEATLAA NTPPERSRPA KREVRKKEGH
     SHHNFLSVLR RDSSPKRHAV QPSERVHNKE KTLEMTPDSS SASSYEEARF EHSDEMYNKA
     LEVAKKKYHL TQENSTRDNG TTECPRTPMT SLMSTNVSSD TAESTLLGTP VYSSNAPFDR
     SPQPSSGCET GNTTPKSIPR RPSFLDKLVR FSQEKYGYRP RRSISSQGHK AEHEHVFTDD
     IPPLPDIPLV DPMQVKPKDV PLPTVEPALG PTDVSPARVA DPESNIETPR TLAPARSSIS
     SSPRRSSPPQ AFQELVPLQS TQSETTGDLA DALALGDNSL DLLPGRVSEI SPKTSFEHFV
     LAPEVPETDE KPAAAPAVAA EAPLSNPPSV VVVPSATSSV PAAQGAAPGV AVTEGPSLGG
     PAAPVRALHA TKTAAAPAKK RSFFHKLFKK Y