ID   MSC3_KLULA              Reviewed;         652 AA.
AC   Q6CK58;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Meiotic sister-chromatid recombination protein 3;
GN   Name=MSC3; OrderedLocusNames=KLLA0F13354g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in the control of meiotic sister-chromatid
CC       recombination. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Peripheral membrane protein.
CC       Note=Cell periphery. {ECO:0000250}.
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DR   EMBL; CR382126; CAG98389.1; -; Genomic_DNA.
DR   RefSeq; XP_455681.1; XM_455681.1.
DR   AlphaFoldDB; Q6CK58; -.
DR   STRING; 28985.XP_455681.1; -.
DR   EnsemblFungi; CAG98389; CAG98389; KLLA0_F13354g.
DR   GeneID; 2896018; -.
DR   KEGG; kla:KLLA0_F13354g; -.
DR   eggNOG; ENOG502RZHH; Eukaryota.
DR   HOGENOM; CLU_487610_0_0_1; -.
DR   InParanoid; Q6CK58; -.
DR   OMA; INGYEYV; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cell membrane; DNA recombination; Meiosis; Membrane; Reference proteome.
FT   CHAIN           1..652
FT                   /note="Meiotic sister-chromatid recombination protein 3"
FT                   /id="PRO_0000096594"
FT   REGION          123..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          304..406
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          470..576
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          594..652
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..147
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..357
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        365..381
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        472..486
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        504..576
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        622..640
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   652 AA;  71450 MW;  82E88CAEF199D9FC CRC64;
     MVFGMNLGNR RKATRVPDLS RYDYHYNGSG GNSVNQGDNY LKSHELSADA AFAASARAGS
     LVNYPERGYT NISRANSLRM GHPGQQQQQS SYIPRSYSFT ARGAYAPRTG NVGNRRSVSA
     IPRTGTASSR GVGSRTGSMT GSVARVGSRT GSFAGGGNGS IIIKTQEVKD MMGRTQSITT
     QTIRRINGME YVETTTQTAG LVEDPQFHFQ QFAENDEFPI SDELSATPPA APLSESQPRT
     NQRLANFNSN AINNSAANNI RSDSEEEGEE HFTDASDVVE ESGAFAEDDQ DHFLAKVNKV
     DVDNNSKSYT SRKPLVQKQG VQQQQEVQHQ GISQVQNTEA KSVGRKSTMS KRMTLRDTPN
     AQLEPEKDTT DQATPDNNAT KRKSIFKSKK RNEAVAVPTV PTSDQKTLSQ EEMYAIALEI
     AQQKYGHPTK TVSHSTDNGS RNEMTPILED ADVEQPHVLP TTLHLPTREE QIQHEQLQQP
     TAAIPTNEKS RHPKKKVKSI LDRVVQFSQE NSGNQPPKQH RGKQYSQQPP DVAPSNGTTD
     NFDTNASGHN INHNNNNHNN NNNTSSSSSL RHESGANPVV VTEDTTVLAA STAATPVDVN
     EPGNPDHVIP ASSPSIDNTP RINEKTKSKK KNEKGSFFKR LFKSNKTHIN TK