ID   MSC6_KLULA              Reviewed;         708 AA.
AC   Q6CTF5;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Meiotic sister-chromatid recombination protein 6, mitochondrial;
DE   Flags: Precursor;
GN   Name=MSC6; OrderedLocusNames=KLLA0C13101g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: May be involved in the control of meiotic sister-chromatid
CC       recombination. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
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DR   EMBL; CR382123; CAH01635.1; -; Genomic_DNA.
DR   RefSeq; XP_452784.1; XM_452784.1.
DR   AlphaFoldDB; Q6CTF5; -.
DR   SMR; Q6CTF5; -.
DR   STRING; 28985.XP_452784.1; -.
DR   EnsemblFungi; CAH01635; CAH01635; KLLA0_C13101g.
DR   GeneID; 2891838; -.
DR   KEGG; kla:KLLA0_C13101g; -.
DR   eggNOG; ENOG502QW5R; Eukaryota.
DR   HOGENOM; CLU_398067_0_0_1; -.
DR   InParanoid; Q6CTF5; -.
DR   OMA; WVKYLET; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
PE   3: Inferred from homology;
KW   DNA recombination; Meiosis; Mitochondrion; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..15
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..708
FT                   /note="Meiotic sister-chromatid recombination protein 6,
FT                   mitochondrial"
FT                   /id="PRO_0000043075"
FT   REGION          19..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..39
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   708 AA;  79667 MW;  9A74C9B191410588 CRC64;
     MLSVRISARQ CSVRGLATQA NNVSQPAKDN ATNGSDAATE KKGTARYQRI QPSVALNSLK
     TKLSNDFQKQ QPAQKIYSQF QSDLQQLISE QQVNPRHFVN SSICNSVLAK LILQSKSELD
     GQSIGESASI PPTPFEILET YLKYNLARHQ HFIIVLKQFL IDLQPKEAIN LWISFLEHAK
     QMPLNNTGTS QVQALTSIAY LMLSKESNSA PDVNVLTQLL NITPSKVPFL AIEQEIKSLG
     LTATTKDELL KSFDDLLLQW FTADKDAFIN EFLKNSNDLK LITYLWKQYL KLATKDFTTS
     NQEIPGAFMI KLAQLDRSLD AVKIMTQLKE ASADFKPSVS LYNSLLQTVA YIPAFGKEAQ
     SIKLNRIQAI WNSYIKSSGN ITVASYKAML EALIIAGHFK TVESFWTLDV PDDVKANSEI
     SDIYLKNFFA SVKKVHFSQL KSKIPSKVHN LELANTILLA MVHSDASVGD IDSFYSHTFQ
     STEGIKPNDK TLAIKLRANL AAFGDSKNES ILGTIGLSAN SPTATLVIEE FLKICENEES
     ATALLKALNI DNKSNDSAKK VSNFLDYYLQ HGNWEYAEEL FKKYLTDNVK SPSSVNYRLF
     NSMFKGFSEL SITRNDTGFV SKQQVYWELC QRIHNRIFNE CVISTLKSVS ALSRRNAEFS
     ENELDFINNT VLPYLVKLKI ENSFKLQNPK YLQNMKSNDK IHIPKELL