MSD1_MOUSE
ID MSD1_MOUSE Reviewed; 278 AA.
AC Q8BIL2;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 100.
DE RecName: Full=Myb/SANT-like DNA-binding domain-containing protein 1;
GN Name=Msantd1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Retina;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK044284; BAC31855.1; -; mRNA.
DR EMBL; BC116928; AAI16929.1; -; mRNA.
DR EMBL; BC116930; AAI16931.1; -; mRNA.
DR CCDS; CCDS19221.1; -.
DR RefSeq; NP_001297479.1; NM_001310550.1.
DR RefSeq; NP_997160.1; NM_207277.1.
DR AlphaFoldDB; Q8BIL2; -.
DR SMR; Q8BIL2; -.
DR STRING; 10090.ENSMUSP00000057362; -.
DR iPTMnet; Q8BIL2; -.
DR PhosphoSitePlus; Q8BIL2; -.
DR PaxDb; Q8BIL2; -.
DR PeptideAtlas; Q8BIL2; -.
DR PRIDE; Q8BIL2; -.
DR ProteomicsDB; 291417; -.
DR Antibodypedia; 57468; 49 antibodies from 8 providers.
DR Ensembl; ENSMUST00000050535; ENSMUSP00000057362; ENSMUSG00000051246.
DR GeneID; 403174; -.
DR KEGG; mmu:403174; -.
DR UCSC; uc008xde.1; mouse.
DR CTD; 345222; -.
DR MGI; MGI:2684990; Msantd1.
DR VEuPathDB; HostDB:ENSMUSG00000051246; -.
DR eggNOG; KOG4282; Eukaryota.
DR GeneTree; ENSGT00390000002245; -.
DR HOGENOM; CLU_086694_0_0_1; -.
DR InParanoid; Q8BIL2; -.
DR OMA; FQFRRLK; -.
DR OrthoDB; 1177523at2759; -.
DR PhylomeDB; Q8BIL2; -.
DR TreeFam; TF331923; -.
DR BioGRID-ORCS; 403174; 1 hit in 71 CRISPR screens.
DR PRO; PR:Q8BIL2; -.
DR Proteomes; UP000000589; Chromosome 5.
DR RNAct; Q8BIL2; protein.
DR Bgee; ENSMUSG00000051246; Expressed in retinal neural layer and 59 other tissues.
DR ExpressionAtlas; Q8BIL2; baseline and differential.
DR GO; GO:0016604; C:nuclear body; IBA:GO_Central.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR026095; Myb/SANT-like_DNA-bd_dom_prot.
DR InterPro; IPR044822; Myb_DNA-bind_4.
DR PANTHER; PTHR22666; PTHR22666; 1.
DR Pfam; PF13837; Myb_DNA-bind_4; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..278
FT /note="Myb/SANT-like DNA-binding domain-containing protein
FT 1"
FT /id="PRO_0000321820"
FT DOMAIN 44..131
FT /note="Myb-like"
FT REGION 139..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 278 AA; 32153 MW; A4A16CA4E2C358B4 CRC64;
MVRWPGLRPC LSAILNPAGA SNMAAAEVPG YLVSPQTEKH RRARNWTDAE MRGLMLVWEE
FFDELKQTKR NAKVYEKMAS KLFEMTGERR LGEEIKIKIT NMTFQYRKLK CMTDSESIPP
DWPYYLAIDR ILAKVPESCE GKLPDGQQPG PSTSQTEASL SPSAKSTPLY LPYTQCSYEG
HFEDDRSDSS SSLLSLKFRS EERPVKKRKM RSCHLQKKKL RLLEAMLEEQ RRLSRAMEET
CREVRRVLDQ QNILQVQSLQ LQERMMSLLE KIIAKSNV
