MSD4_MOUSE
ID MSD4_MOUSE Reviewed; 345 AA.
AC Q91YU3;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Myb/SANT-like DNA-binding domain-containing protein 4;
GN Name=Msantd4;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryo;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK132023; BAE20948.1; -; mRNA.
DR EMBL; BC014729; AAH14729.1; -; mRNA.
DR CCDS; CCDS22796.1; -.
DR RefSeq; NP_663584.1; NM_145609.1.
DR RefSeq; XP_006509954.1; XM_006509891.3.
DR AlphaFoldDB; Q91YU3; -.
DR SMR; Q91YU3; -.
DR BioGRID; 219159; 2.
DR STRING; 10090.ENSMUSP00000038267; -.
DR iPTMnet; Q91YU3; -.
DR PhosphoSitePlus; Q91YU3; -.
DR EPD; Q91YU3; -.
DR MaxQB; Q91YU3; -.
DR PaxDb; Q91YU3; -.
DR PeptideAtlas; Q91YU3; -.
DR PRIDE; Q91YU3; -.
DR ProteomicsDB; 291353; -.
DR Antibodypedia; 54341; 31 antibodies from 10 providers.
DR DNASU; 78100; -.
DR Ensembl; ENSMUST00000047173; ENSMUSP00000038267; ENSMUSG00000041124.
DR Ensembl; ENSMUST00000212075; ENSMUSP00000148805; ENSMUSG00000041124.
DR GeneID; 78100; -.
DR KEGG; mmu:78100; -.
DR UCSC; uc009obm.1; mouse.
DR CTD; 84437; -.
DR MGI; MGI:1925350; Msantd4.
DR VEuPathDB; HostDB:ENSMUSG00000041124; -.
DR eggNOG; ENOG502RGM9; Eukaryota.
DR GeneTree; ENSGT00440000039469; -.
DR HOGENOM; CLU_066150_0_0_1; -.
DR InParanoid; Q91YU3; -.
DR OMA; MGFAIES; -.
DR OrthoDB; 1027153at2759; -.
DR PhylomeDB; Q91YU3; -.
DR TreeFam; TF330965; -.
DR BioGRID-ORCS; 78100; 0 hits in 57 CRISPR screens.
DR ChiTaRS; Msantd4; mouse.
DR PRO; PR:Q91YU3; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q91YU3; protein.
DR Bgee; ENSMUSG00000041124; Expressed in substantia nigra and 246 other tissues.
DR Genevisible; Q91YU3; MM.
DR GO; GO:0005634; C:nucleus; ISO:MGI.
DR InterPro; IPR026162; MSANTD4.
DR InterPro; IPR028002; Myb_DNA-bind_5.
DR PANTHER; PTHR21732; PTHR21732; 1.
DR Pfam; PF13873; Myb_DNA-bind_5; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Isopeptide bond; Phosphoprotein; Reference proteome;
KW Ubl conjugation.
FT CHAIN 1..345
FT /note="Myb/SANT-like DNA-binding domain-containing protein
FT 4"
FT /id="PRO_0000311831"
FT DOMAIN 4..77
FT /note="Myb-like"
FT REGION 139..175
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 202..344
FT /evidence="ECO:0000255"
FT COMPBIAS 150..164
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 106
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q501L3"
FT MOD_RES 188
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q8NCY6"
FT CROSSLNK 9
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8NCY6"
FT CROSSLNK 114
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8NCY6"
FT CROSSLNK 142
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8NCY6"
FT CROSSLNK 237
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8NCY6"
FT CROSSLNK 254
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8NCY6"
FT CROSSLNK 273
FT /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT G-Cter in SUMO2)"
FT /evidence="ECO:0000250|UniProtKB:Q8NCY6"
SQ SEQUENCE 345 AA; 41247 MW; A3EDF0DD570B65FB CRC64;
MKQLKRKRKS NFSVQETQTL LKEITKRKEV IFSKQLNTTI NVMKRMAWEE IAQCVNAVGE
GEQRTGTEVK RRYLDWRALM KRKRMKANMK LVGSGFPLPT SDLDDSLTED IDEKIAFRND
ANFEWQNVAD FRDAGGSLTE VKVEEEERDP QSPEFEIEEE EEMLSSVIPD SRRENELPDF
PHIDEFFTLN STPSRPTYDE PHLLMNIEKQ KLELEKRRLD IEAERLQVEK ERLQIEKERL
RHLDLEHERL QLEKERLQIE REKWRLQLVS TEKPALENEL GQGEKSMLQP QDIEAEKLKL
ERERLQLEKD RLQFLKFESE KLQIEKERLQ VEKERLRIQK EGHLP
