ID   MSP1_PLAFN              Reviewed;         281 AA.
AC   P13820;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Merozoite surface protein 1;
DE   AltName: Full=Merozoite surface antigens;
DE   AltName: Full=PMMSA;
DE   Flags: Precursor; Fragment;
GN   Name=MSP-1;
OS   Plasmodium falciparum (isolate NF7 / Ghana).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=5842;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=2449612; DOI=10.1016/0166-6851(88)90049-7;
RA   Peterson M.G., Coppel R.L., McIntyre P., Langford C.J., Woodrow G.,
RA   Brown G.V., Anders R.F., Kemp D.J.;
RT   "Variation in the precursor to the major merozoite surface antigens of
RT   Plasmodium falciparum.";
RL   Mol. Biochem. Parasitol. 27:291-302(1988).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-
CC       anchor {ECO:0000305}.
CC   -!- PTM: Merozoite surface antigen contain the sequence of 83 kDa, 42 kDa
CC       and 19 kDa antigens which are the major surface antigens of merozoites.
CC       The maturation take place during schizont.
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DR   EMBL; M19144; AAA29654.1; -; mRNA.
DR   PIR; B54498; B54498.
DR   AlphaFoldDB; P13820; -.
DR   SMR; P13820; -.
DR   GO; GO:0031225; C:anchored component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; GPI-anchor; Lipoprotein; Malaria; Membrane;
KW   Merozoite; Repeat; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..>281
FT                   /note="Merozoite surface protein 1"
FT                   /id="PRO_0000024558"
FT   REGION          63..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..118
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        109
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        248
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   NON_TER         281
SQ   SEQUENCE   281 AA;  31226 MW;  6150B76E0F21B299 CRC64;
     MKIIFFLCSF LFFIINTQCV THESYQELVK KLEALEDAVL TGYSLFQKEK MVLNEEEITT
     KGASAQSGAS AQSGASAQSG ASAQSGTSGP SGPSGTSPSS RSNTLPRSNT SSGASPPADA
     SDSDAKSYAD LKHRVRNYLF TIKQLKYPES LDLPNHMLTL CDNIHGFKYL IDGYEEINEL
     LYKLNFYFSL LRAKLNDVCA NDYCQIPFNL KIRANELDVL KKLVFGYRKP LDNIKDNVGK
     MEDYIKKNKT TIANINELIE GSKKTIDQNK NADNEEGKKK I