ID   MSP2_ONCVO              Reviewed;         127 AA.
AC   P13263;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Major sperm protein 2;
DE            Short=MSP2;
OS   Onchocerca volvulus.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=6282;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2770787; DOI=10.1016/0166-6851(89)90184-9;
RA   Scott A.L., Dinman J., Sussman D.J., Yenbutr P., Ward S.;
RT   "Major sperm protein genes from Onchocerca volvulus.";
RL   Mol. Biochem. Parasitol. 36:119-126(1989).
CC   -!- FUNCTION: Central component in molecular interactions underlying sperm
CC       crawling. Forms an extensive filament system that extends from sperm
CC       villipoda, along the leading edge of the pseudopod.
CC   -!- SUBCELLULAR LOCATION: Cell projection, pseudopodium. Cytoplasm,
CC       cytoskeleton.
CC   -!- TISSUE SPECIFICITY: Sperm.
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DR   EMBL; J04663; AAA29421.1; -; Genomic_DNA.
DR   PIR; B45528; B45528.
DR   AlphaFoldDB; P13263; -.
DR   SMR; P13263; -.
DR   STRING; 6282.P13263; -.
DR   HOGENOM; CLU_120664_0_1_1; -.
DR   Proteomes; UP000024404; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000535; MSP_dom.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..127
FT                   /note="Major sperm protein 2"
FT                   /id="PRO_0000213458"
FT   DOMAIN          9..126
FT                   /note="MSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00132"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   127 AA;  14356 MW;  B2FF9552D391C224 CRC64;
     MAQSVPPGDI HTQPGSKIVF NAPYDDKHTY HIKITNAGGR RIGWAIKTTN MKRLGVDPPC
     GVLDPKENVL MAVSCDTFDA TREDINNDRI TIEWTNTPDG AAKQFRREWF QGDGMVRRKN
     LPIEYNL