ID   MSP49_CAEEL             Reviewed;         127 AA.
AC   Q18461;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Major sperm protein 49;
DE            Short=MSP;
GN   Name=msp-49; ORFNames=C34F11.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Central component in molecular interactions underlying sperm
CC       crawling. Forms an extensive filament system that extends from sperm
CC       villipoda, along the leading edge of the pseudopod.
CC   -!- SUBCELLULAR LOCATION: Cell projection, pseudopodium. Cytoplasm,
CC       cytoskeleton.
CC   -!- TISSUE SPECIFICITY: Sperm.
CC   -!- MISCELLANEOUS: Around 30 MSP isoforms may exist in C.elegans.
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DR   EMBL; FO080689; CCD65826.1; -; Genomic_DNA.
DR   PIR; F88146; F88146.
DR   RefSeq; NP_494970.1; NM_062569.5.
DR   AlphaFoldDB; Q18461; -.
DR   SMR; Q18461; -.
DR   STRING; 6239.C34F11.6; -.
DR   PaxDb; Q18461; -.
DR   PeptideAtlas; Q18461; -.
DR   EnsemblMetazoa; C34F11.6.1; C34F11.6.1; WBGene00003442.
DR   UCSC; C34F11.6; c. elegans.
DR   WormBase; C34F11.6; CE04166; WBGene00003442; msp-49.
DR   eggNOG; ENOG502RXF6; Eukaryota.
DR   GeneTree; ENSGT00970000195833; -.
DR   HOGENOM; CLU_120664_0_1_1; -.
DR   InParanoid; Q18461; -.
DR   OrthoDB; 1405423at2759; -.
DR   PhylomeDB; Q18461; -.
DR   PRO; PR:Q18461; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00003442; Expressed in material anatomical entity and 2 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000535; MSP_dom.
DR   InterPro; IPR008962; PapD-like_sf.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000250"
FT   CHAIN           2..127
FT                   /note="Major sperm protein 49"
FT                   /id="PRO_0000213441"
FT   DOMAIN          9..126
FT                   /note="MSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00132"
FT   MOD_RES         2
FT                   /note="N-acetylalanine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   127 AA;  14221 MW;  53D359DB8EA5AB74 CRC64;
     MAQSVPPGDI QTQPGTKIVF NAPYDDKHTY HIKVINSSAR RIGYGIKTIN MKRLGVDPPC
     GVLDPKEAVL LAVSCDAFAF GQEDTNNDRI TVEWTNTPDG AAKQFRREWF QGDGMVRRKN
     LPIEYNP