ID   MSPA_TREMA              Reviewed;         575 AA.
AC   Q9Z4I3;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Major outer membrane protein MspA;
DE   AltName: Full=Major sheath protein;
DE   Flags: Precursor;
GN   Name=mspA;
OS   Treponema maltophilum.
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=51160;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 20-34.
RC   STRAIN=ATCC 51939 / DSM 27366 / CIP 105146 / OMZ 679 / BR;
RX   PubMed=9922270; DOI=10.1128/jb.181.3.1025-1029.1999;
RA   Heuner K., Choi B.-K., Schade R., Moter A., Otto A., Goebel U.B.;
RT   "Cloning and characterization of a gene (mspA) encoding the major sheath
RT   protein of Treponema maltophilum ATCC 51939(T).";
RL   J. Bacteriol. 181:1025-1029(1999).
RN   [2]
RP   SUBCELLULAR LOCATION.
RX   PubMed=11313133; DOI=10.1111/j.1574-6968.2001.tb10602.x;
RA   Heuner K., Meltzer U., Choi B.-K., Goebel U.B.;
RT   "Outer sheath associated proteins of the oral spirochete Treponema
RT   maltophilum.";
RL   FEMS Microbiol. Lett. 197:187-193(2001).
CC   -!- FUNCTION: Major component of the outer membrane sheath.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane
CC       {ECO:0000269|PubMed:11313133}; Peripheral membrane protein
CC       {ECO:0000269|PubMed:11313133}.
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DR   EMBL; Y17800; CAA76862.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q9Z4I3; -.
DR   PRIDE; Q9Z4I3; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR036709; Autotransporte_beta_dom_sf.
DR   SUPFAM; SSF103515; SSF103515; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Direct protein sequencing; Membrane; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000269|PubMed:9922270"
FT   CHAIN           20..575
FT                   /note="Major outer membrane protein MspA"
FT                   /id="PRO_0000021771"
SQ   SEQUENCE   575 AA;  62250 MW;  C666B188F5DE16A0 CRC64;
     MKKALVFFVA LAMIGSVFAA EPAAEAKVAE FSGNAAVTFG FDLDTVKAGF KNTTEADLKF
     NLMNGGDKST TGNGVWGELK LVVNALQIRA TADVSDGHTF AIQTKKDNDG EDTIFVEIDT
     AKLHFNDLYV GITSGDFRYG GSFWYPNALN YKDSKEDEKY TRSRAAKLGY DQGLVLGYEK
     KDLFKVELAA RSKKDTTKKV EKVELVHLSA GAKIKEKEYY KTEPAAVTGD TAQDIFNDGT
     LVSVTADPKV KTLNAEGAYY KPVMKDDETN YWTNKFALGL YGEVTPIKDL RIGVGAAYVL
     GQLGAAASED DKTNDISVFA GVDYRFNFNE DFFIQPTVTY NFYNDYKVAS KNYAIETNKM
     NAGLRFGFAK SKSDSENESL LYTFFGQEKL FYETTKNDKG DQILLPGVSV FGSFNFKENA
     MKTELPVMLT FYSGELVQNL KAYALFGANL GPDAGKGTAV AMSDAVYKGI IEKKGMQAGL
     AASYDVKVND AVTIVPAAGV LWTHGSQASG NDKMSADEVA VSLKADVKGL VSNTTFTAFW
     EKASFGKGAA SVGGTKTSVD AVKKGVIGLK AKIAL