ID   MSPD3_BOVIN             Reviewed;         235 AA.
AC   Q3T033;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Motile sperm domain-containing protein 3;
GN   Name=MOSPD3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; BC102592; AAI02593.1; -; mRNA.
DR   RefSeq; NP_001029437.1; NM_001034265.2.
DR   RefSeq; XP_005225086.1; XM_005225029.3.
DR   RefSeq; XP_010817795.1; XM_010819493.1.
DR   RefSeq; XP_010817796.1; XM_010819494.2.
DR   AlphaFoldDB; Q3T033; -.
DR   SMR; Q3T033; -.
DR   PaxDb; Q3T033; -.
DR   PRIDE; Q3T033; -.
DR   GeneID; 506163; -.
DR   KEGG; bta:506163; -.
DR   CTD; 64598; -.
DR   eggNOG; KOG0439; Eukaryota.
DR   HOGENOM; CLU_088040_0_0_1; -.
DR   InParanoid; Q3T033; -.
DR   OrthoDB; 1197131at2759; -.
DR   TreeFam; TF319778; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0033149; F:FFAT motif binding; IBA:GO_Central.
DR   GO; GO:0090158; P:endoplasmic reticulum membrane organization; IBA:GO_Central.
DR   GO; GO:0061817; P:endoplasmic reticulum-plasma membrane tethering; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000535; MSP_dom.
DR   InterPro; IPR008962; PapD-like_sf.
DR   InterPro; IPR016763; VAP.
DR   PANTHER; PTHR10809; PTHR10809; 1.
DR   Pfam; PF00635; Motile_Sperm; 1.
DR   SUPFAM; SSF49354; SSF49354; 1.
DR   PROSITE; PS50202; MSP; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..235
FT                   /note="Motile sperm domain-containing protein 3"
FT                   /id="PRO_0000248064"
FT   TRANSMEM        180..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          33..145
FT                   /note="MSP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00132"
FT   REGION          1..30
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          143..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        151..170
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   235 AA;  25654 MW;  548BD7DF3FD7B977 CRC64;
     MRRGAPQDQE LVGPGAPGRG SRGAPPPSGP VVPVLVFPPD LVFRADQRSG PRQLLTLYNP
     TGAVLRFRVL CTAPAKYTVF DAEGYVKPQS CIDIVIRHVA PHPRNYDVQD RFRIELSEEG
     TEGRVVGRKD ITSVLRAPAY PLELQGQSDP TPHPEPHSWT ASSTAQPFPE NPHPQLATSS
     FLLFLLMGTV SVAFLLLPLQ DELGSQLPQI LHVSLGQKLV AAYVLGLLTM VFLRT