ID   MSS11_KLULA             Reviewed;         539 AA.
AC   Q6CPW4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Transcription activator MSS11;
GN   Name=MSS11; OrderedLocusNames=KLLA0E01716g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Transcription factor that regulates pseudohyphal
CC       differentiation, invasive growth, floculation, adhesion and starch
CC       metabolism in response to nutrient availability. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MSS11 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99112.1; -; Genomic_DNA.
DR   RefSeq; XP_454025.1; XM_454025.1.
DR   AlphaFoldDB; Q6CPW4; -.
DR   SMR; Q6CPW4; -.
DR   STRING; 28985.XP_454025.1; -.
DR   PRIDE; Q6CPW4; -.
DR   EnsemblFungi; CAG99112; CAG99112; KLLA0_E01717g.
DR   GeneID; 2893689; -.
DR   KEGG; kla:KLLA0_E01717g; -.
DR   eggNOG; ENOG502S549; Eukaryota.
DR   HOGENOM; CLU_505333_0_0_1; -.
DR   InParanoid; Q6CPW4; -.
DR   OMA; EWWQSLW; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0031326; P:regulation of cellular biosynthetic process; IEA:UniProt.
DR   InterPro; IPR006594; LisH.
DR   Pfam; PF08513; LisH; 1.
DR   SMART; SM00667; LisH; 1.
DR   PROSITE; PS50896; LISH; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..539
FT                   /note="Transcription activator MSS11"
FT                   /id="PRO_0000333385"
FT   DOMAIN          51..83
FT                   /note="LisH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00126"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..331
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          396..452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          477..517
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        177..226
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..248
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        258..331
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   539 AA;  60626 MW;  C9213D2D690C4E64 CRC64;
     MAGPGARKSN ASNTPQDKKM KGDSIQDQKN KQYNSGDVVE PFVSDAMAKN SKQLLYAHIY
     NYLVHNQHHD TAKKFLQEAN VPLSKAVPQH SLNGDKLLNS KMLMNSPDTF LFEWWQSLWA
     LNQYVETTPI ENLTSLKPFN DRIVPILPQV PPQEMLSRVV RTGPIAPAMG FAGNIVPQQQ
     QQQQQQQQQQ LQQQQQQQQH FRTMTSPGSG NTPYATNANS FPAGVRVPQP QGSFQPVLGT
     TPNAGTNAGL GVNPYHAATL GSSKSTPKPQ NTSVGSKNKQ TKKSSATNKD SGANTKPRAN
     GESKQFKGVN SSSKVKKPSP SGSQQVQANW TKLQQKQQQQ QQQQQQQQQQ QQQQQQQQQQ
     HQQQQQHQQQ QQHQQQQQHQ QQQQQIRMQY QKMMTLMQHQ QNQQNQQHHQ LGNQNILPGQ
     GDPSDNSSPS QQYLQQQRAY ENMVKSQQQD QPMNKDHFAM SLQTQQPQSF DSYAMPATMG
     PQASSQPLDN NKKSEPLSKI DVTNNQDFNT FSGGSNNKLN FGQFDMSGLG NEFMGGRKQ