MSS18_YEAST
ID MSS18_YEAST Reviewed; 268 AA.
AC P08593; D6W4D1;
DT 01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1988, sequence version 1.
DT 03-AUG-2022, entry version 153.
DE RecName: Full=Protein MSS18;
GN Name=MSS18; OrderedLocusNames=YPR134W; ORFNames=P9659.8;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC STRAIN=ATCC 204510 / AB320;
RX PubMed=2842150; DOI=10.1002/j.1460-2075.1988.tb02963.x;
RA Seraphin B., Simon M., Faye G.;
RT "MSS18, a yeast nuclear gene involved in the splicing of intron aI5 beta of
RT the mitochondrial cox1 transcript.";
RL EMBO J. 7:1455-1464(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [6]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 76625 / YPH499;
RX PubMed=14576278; DOI=10.1073/pnas.2135385100;
RA Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R.P., Meyer H.E.,
RA Schoenfisch B., Perschil I., Chacinska A., Guiard B., Rehling P.,
RA Pfanner N., Meisinger C.;
RT "The proteome of Saccharomyces cerevisiae mitochondria.";
RL Proc. Natl. Acad. Sci. U.S.A. 100:13207-13212(2003).
CC -!- FUNCTION: Involved in splicing of intron aI5-beta of the mitochondrial
CC COX1 transcript. {ECO:0000269|PubMed:2842150}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:14562095,
CC ECO:0000269|PubMed:14576278}.
CC -!- MISCELLANEOUS: Present with 861 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: To baculovirus occlusion-derived virus envelope protein E27
CC (ODV-E27). {ECO:0000305}.
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DR EMBL; X07650; CAA30490.1; -; Genomic_DNA.
DR EMBL; U40829; AAB68275.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11547.1; -; Genomic_DNA.
DR PIR; S00553; S00553.
DR RefSeq; NP_015460.1; NM_001184231.1.
DR AlphaFoldDB; P08593; -.
DR SMR; P08593; -.
DR BioGRID; 36301; 224.
DR DIP; DIP-5396N; -.
DR MINT; P08593; -.
DR STRING; 4932.YPR134W; -.
DR MaxQB; P08593; -.
DR PaxDb; P08593; -.
DR PRIDE; P08593; -.
DR EnsemblFungi; YPR134W_mRNA; YPR134W; YPR134W.
DR GeneID; 856253; -.
DR KEGG; sce:YPR134W; -.
DR SGD; S000006338; MSS18.
DR VEuPathDB; FungiDB:YPR134W; -.
DR eggNOG; ENOG502S6W5; Eukaryota.
DR HOGENOM; CLU_090748_0_0_1; -.
DR InParanoid; P08593; -.
DR OMA; KFIQNNC; -.
DR BioCyc; YEAST:G3O-34270-MON; -.
DR PRO; PR:P08593; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; P08593; protein.
DR GO; GO:0005739; C:mitochondrion; HDA:SGD.
DR GO; GO:0000372; P:Group I intron splicing; IDA:SGD.
DR GO; GO:0090615; P:mitochondrial mRNA processing; IMP:SGD.
PE 1: Evidence at protein level;
KW Mitochondrion; mRNA processing; mRNA splicing; Reference proteome.
FT CHAIN 1..268
FT /note="Protein MSS18"
FT /id="PRO_0000096602"
SQ SEQUENCE 268 AA; 30957 MW; 4D0288A25FAF6F4E CRC64;
MGLPEVNFLR KNCILVELKL FYQTVYPPKE LYWNNRITAE LSTFSNIKYA RPTFAVNNGT
FQRTRPKLDL VLASSDIRKL ATVLFNLKAL IMNTKGEEPT LTTMTSVQTN EEKNDNLEQK
YSSLLDRWNG KVEVHDSPFL QLQRDSNLLF AERPVRYVST TEGEGVDISS EEFFRLEEEQ
CRRNYDVLVD EHSTPSVGMK DGQYGPNIIH FEPSLYHTYS SLPMSMKFWL NGLEDDETTM
MNIDEKSAEN LDILLHGFKG FSNKRVKG
