MSS51_MOUSE
ID MSS51_MOUSE Reviewed; 446 AA.
AC Q9D5Z5; Q0VD61;
DT 10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Putative protein MSS51 homolog, mitochondrial;
DE AltName: Full=Zinc finger MYND domain-containing protein 17;
GN Name=Mss51; Synonyms=Zmynd17;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Head;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- CAUTION: Although no clear MSS51 ortholog is encoded in mammalian
CC genomes, the mammalian MSS51/ZMYND17 protein is significantly similar.
CC Considered by a number of resources to be the ortholog of yeast MSS51.
CC {ECO:0000305}.
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DR EMBL; AK014794; BAB29556.1; -; mRNA.
DR EMBL; BC119773; AAI19774.1; -; mRNA.
DR EMBL; BC119816; AAI19817.1; -; mRNA.
DR CCDS; CCDS49414.1; -.
DR RefSeq; NP_083380.1; NM_029104.1.
DR AlphaFoldDB; Q9D5Z5; -.
DR STRING; 10090.ENSMUSP00000022353; -.
DR PaxDb; Q9D5Z5; -.
DR PRIDE; Q9D5Z5; -.
DR ProteomicsDB; 287507; -.
DR Antibodypedia; 29415; 104 antibodies from 18 providers.
DR Ensembl; ENSMUST00000022353; ENSMUSP00000022353; ENSMUSG00000021815.
DR GeneID; 74843; -.
DR KEGG; mmu:74843; -.
DR UCSC; uc007sjw.2; mouse.
DR CTD; 118490; -.
DR MGI; MGI:1922093; Mss51.
DR VEuPathDB; HostDB:ENSMUSG00000021815; -.
DR eggNOG; ENOG502QVEJ; Eukaryota.
DR GeneTree; ENSGT00940000153820; -.
DR HOGENOM; CLU_047718_0_0_1; -.
DR InParanoid; Q9D5Z5; -.
DR OMA; ANPFMSL; -.
DR OrthoDB; 550249at2759; -.
DR PhylomeDB; Q9D5Z5; -.
DR TreeFam; TF330829; -.
DR BioGRID-ORCS; 74843; 1 hit in 72 CRISPR screens.
DR ChiTaRS; Mss51; mouse.
DR PRO; PR:Q9D5Z5; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; Q9D5Z5; protein.
DR Bgee; ENSMUSG00000021815; Expressed in knee joint and 113 other tissues.
DR Genevisible; Q9D5Z5; MM.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR002893; Znf_MYND.
DR Pfam; PF01753; zf-MYND; 1.
DR PROSITE; PS01360; ZF_MYND_1; 1.
DR PROSITE; PS50865; ZF_MYND_2; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..446
FT /note="Putative protein MSS51 homolog, mitochondrial"
FT /id="PRO_0000218318"
FT ZN_FING 104..148
FT /note="MYND-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 104
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 107
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 123
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 126
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 132
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 136
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 144
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
FT BINDING 148
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00134"
SQ SEQUENCE 446 AA; 49950 MW; 055C144CC5628DB3 CRC64;
MAPRSRRRKH KKPPPVIPMI EIPPTEVSPV SPALSKPGPS IDALGFISLD NNVPGLSQLI
LQKLNMKNYE EYKLVINGGT PVSSFGFRCQ QEMFQKMEDT FRFCAYCKVL PHGLSNCKVL
RHCKRCRNVY YCDTECQRSD WPAHRKVCRE LRLVAVDRVM EWLLVTGDFV LPSGPWPWLP
EDIQNWDTWF SMRGLQLEST LNALLGSHSM TMLWASLGRP RPDPDVLHGS LKRLMTDVLS
RPLTLGLGLR TVAIDVGKTG GSTLHVVGAS HVETFLIRSG DYDELGYMFP EHLGFHVIMV
GVDVATDLLQ SSSSLSLEPG TIQLSGHRAL YHDFWEEQIE TGILAHPDLV AAFHPGFHAS
PGLMEAWLPT LLLLRDYEIP TLITVYSQQE LEASLQILVN LDTHIIACGA NPFASLKPEQ
VYSNPNKQPV YSSAYYIMFL GSSPAN
